ID A0A1V9XJA3_9ACAR Unreviewed; 2629 AA.
AC A0A1V9XJA3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 13-SEP-2023, entry version 22.
DE RecName: Full=FH1/FH2 domain-containing protein 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BIW11_09668 {ECO:0000313|EMBL:OQR73536.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR73536.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR73536.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR73536.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR73536.1}.
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DR EMBL; MNPL01009763; OQR73536.1; -; Genomic_DNA.
DR STRING; 418985.A0A1V9XJA3; -.
DR InParanoid; A0A1V9XJA3; -.
DR OrthoDB; 2918313at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR041387; FHOD1_GBD_N.
DR InterPro; IPR014768; GBD/FH3_dom.
DR PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR PANTHER; PTHR45920:SF4; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR Pfam; PF02181; FH2; 1.
DR Pfam; PF18382; Formin_GBD_N; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000192247}.
FT DOMAIN 1414..1845
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 2099..2491
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 52..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1122..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1191..1298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1767..1799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1899..1918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2023..2105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2469..2520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2536..2571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2584..2629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..651
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..756
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..777
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..875
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..973
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2036..2054
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2073..2105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2469..2497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2548..2565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2597..2622
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2629 AA; 294845 MW; 0D964EECA1462051 CRC64;
MSNRYGGYYP SYRRTTSPSF SSQFNSFGFG SASTYRPSAS FASATSSIAS KYQSAGNATK
SSGSGPLYPY RAPTNSEYTS DHAKSGHLSD TSRASGYASE TKKPPPGKTN TGYASDASRS
GYNSDARTPP NSYARVQSNS YERPPSYSRS VYDSYKTTSG DRYAPHYSSK TILTRQNSVP
PKDRSPSPGV YQWQASSQDL AAQRPYQRQD KAANFGSRTN LQRQDSNELS CHDNPRDYQS
VTYGSRPPLQ RQGSVGDRAT SANASRPSFQ RQDSAPGNYS QRNERTTDYG FPSRGGSLKF
PERSEHALAT TNRDYKNTLS RGDIPSRRGS VVGNSGTYQS DRSRAASPAG SPSPLVRQAA
YEGSRIASEL SSVAKAIQQF SLTPKPTLPQ SWRPSSAYQP FETPSRRVYY IPPNRSPYSS
LSRTSSYKTP EPKPNLAPAD FCNSDSEDSD SDAEEKLEYL ICRSTSPSTT YRPEDENMIS
SISKLQKPTR KRFHVGKLCA SVQVDSQDIK KAFAPTLKIT SPERASQSKT SPTDAVPAYV
YYGKFSTATA PSAASITANN KLARPAPGQS PQNSPTSPEK ATESQWVFQT APKKSASPEA
NPEGKRSSRE IRARKNKEEV RENRKSREDS KEYRKNQDHS RENRKSRENI YETATNETIE
NEKQKLVNAN KDFRKSVLNM NLSEKEREEY LKMQKAKRKA LRRAGKPMEK ESDTEILQSS
TEDSECDVSS RREVSRSHSQ RSVHKHDVKR TSSSSRVKGD SESSSASGEE DHSQVRRSFR
RKRPSRGSTL EDRAPSPQEL QSVNQLQELG DSLKADAPLA RGEDDTECEE ELQGDHDVAE
EAMHETPSPS KVPPTAQDET DTSSTSESNS YGIEKSATVV FKGSHEPLTN GDRSPIQRPA
FIKVPSQDRP QEVVYSLKKS DTSPRIEKKE STSSANELTV PSHIQKSHSA EAVTNNVRQS
DIQRPSSSQA HVRLEPANEP PGLARSSEMI DAIDVQEEAS KEQKFRYQPK PLYNRTRDLT
ANVGTPESSD ACTVEKPRIQ LWQESEPVVF SLRTPRPYKS IYKRGSATET ESDAQQVYEN
VNFNRTHSPT KPLQILRLQQ EGDVSSSDYE VVGIPARRKE FVKRRSKEGN ESSRSKETSP
FSDRKSRPNS VIEVAPLERQ DSEPISQAEI DLIQYLQQQQ VQIQRKAEEQ RRYSLQRQRP
KSEDAAATAN RPDVPDSPKG EVDEEQTQQP QRSSSFRSSS RPSWAIHQEA ASSTPWQTAS
ATAAQEGSSM PDRSKQTDAS RFAQSPADGP HGPVQANQHQ AAVTLARFPR QEAPLRKGKS
QFIGTFKDID SFLEFCDSDS FDAMETKFDN EQIQKLEPLS PQIRKSSSRA QISRPNNFIG
NFIDIDEILG PESPSACPFE KSQDAMSLFK VEASQVKVHG PKDSMRSELL PKIEEFDSSA
IRVREVQKGQ GIMSKVDDSC LQLYRHSDEG GAYLDLDSSI EQQRDEFAAF GRDDASIVLR
TQLPVRVHAI IEKLVNSSGR DLRRALFALK QVFQDDKDLV HAFVENRGLD VLVKIGQNSD
HNYQNYILRA LGQVMLYVDG MHGVIKHNQT IQWLYLLTQS NYRLVVKAAL KLLLVFLEYT
GSNCLELLRA MFRVQQTHNL KPWSSVMKIL SQRDNADMEL LIFAMSLINK VEDIELLDTL
ADSLMRFLQV HGYQPPNLPD VASKETLDAV PDQDTYYDIV DSLEEMGMER VVQFYMAKQG
VDNDLLQQLQ LYENILRLED GFASPNTKVP ACVRNRKQNP TRKSRRHNPN DGPPTKIKPS
PLLQNLIRSV EETSFNDGDL TPAMRRWRDD HQMRDYLQDE NSEPMEICGQ GAQGSANVRQ
FKNIFEQTIQ EQEAADAPRR QEVPRRQLID LSALHHAQDN IPKVPDHQPR SLNAAGYSPQ
GLTEKIPNYS PMRPPASLDA SAVSSRQPPY ATQPTFGKIP SNNNQQFSNN LQKFNNLEKD
SILQDMIWKS GSPVQWQDFI KSVRRPLFIN DFDFTDLSEE DDVAVLNDGG GPFGAGGGAP
PPPPPPPPPM AGFGSPFSAR PGAPFGTMGP RGQTPPFLQQ KQHPSSQLPW AANRNEPGAQ
PTIQKNKKTV KLFWKEIKED PMLLARIKKQ HTIWDELARE EIDSARLEEL FENKAKDLMK
QKQEGKKNEI TVLDAKRSNA INIGMTKLPN PRTIRTAILK MDSTIMNREG IEKILTTMIP
QPEEMNKIVE AQMANPDVPL GNAENFLLTL SSITELEPRL RLWAFVLDYN ALEKEVAEPL
MDLKQAIVEI ENNNTFRVIL STVLAIGNFL NGAPVKGFQL DYLAKLPEVK DTVYKHSLLF
HVVEFVSARH PNSSDLYSEM ASVTRSSKVD FEETAKTLNK LETDCKASWE HLKAVAKHDG
QQGLASIATF LSDCAERITV LGIIHKRVIN RFHKLMVYFG HPLYTIKDAK PHAICKVVSE
FALEYRTTRE KIREQSEKKR REAERATRAK RSGLDSRGAT PERASTLPRG VRGGSVKSER
ELTRLLSNGY SSDASDGDYR NWGSLGRRSR AGSVNQMSRH NSIKEGEYMS GTDGDELIES
LMRNATQAPS QRSLERQRRI PTGERRSLRR TLQGDLGREE RRSCPYMSS
//
