ID A0A1V9XLM0_9ACAR Unreviewed; 704 AA.
AC A0A1V9XLM0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=CAP-Gly domain-containing linker protein 4-like {ECO:0000313|EMBL:OQR74379.1};
GN ORFNames=BIW11_09118 {ECO:0000313|EMBL:OQR74379.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR74379.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR74379.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR74379.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Target cell membrane {ECO:0000256|ARBA:ARBA00004175}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR74379.1}.
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DR EMBL; MNPL01008082; OQR74379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9XLM0; -.
DR STRING; 418985.A0A1V9XLM0; -.
DR InParanoid; A0A1V9XLM0; -.
DR OrthoDB; 2914056at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0044231; C:host cell presynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0044218; C:other organism cell membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01302; CAP_GLY; 3.
DR SMART; SM00248; ANK; 3.
DR SMART; SM01052; CAP_GLY; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00845; CAP_GLY_1; 3.
DR PROSITE; PS50245; CAP_GLY_2; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Membrane {ECO:0000256|ARBA:ARBA00023298};
KW Neurotoxin {ECO:0000256|ARBA:ARBA00022699};
KW Presynaptic neurotoxin {ECO:0000256|ARBA:ARBA00023028};
KW Reference proteome {ECO:0000313|Proteomes:UP000192247};
KW Target cell membrane {ECO:0000256|ARBA:ARBA00022537};
KW Target membrane {ECO:0000256|ARBA:ARBA00023298};
KW Toxin {ECO:0000256|ARBA:ARBA00022656}.
FT REPEAT 191..223
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 300..342
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 472..514
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 641..683
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 75966 MW; 37C6A677418330E9 CRC64;
MPTNPGGDVD RSSVGSGNSL GERPQVKITR KHTIVYPSAE APRCPQCESE GLRHFNFSEC
TPCMELLRNE TTTVPQILAM LRHWNPVTQK HMHIIASEIL RRGSNVNDRD GLTDMSLLHY
AAKGGALAGP SVAGQTVTAL LDRGADLKLR CRWTDMTALH YAVFFDVPNV VEILLKAGKR
SDVEATSNDF EGGTSLHIAA ANLNVESAKL LVQYGANVNA TDNLGRIPND VIPPTLDPDL
VPEDAIVTLK DLLRPDSRDE ILASPHTSVS GRVLLQSLGL KIGDQIMVSP NKVGTLRYCG
TIHFATGVWA GVELDEPSGK NDGSLAGVSY FNCPANRGVF VPITKVSRPS QMGSDLHPSP
RRDRIFSFPK LDVSHVTSKV QTEPDPVNAG LPGNREVDQP TAVKSITSDF PLLATEKNSA
TLKDKPCKAL HKSPRLRVGR GASDPSVEPL QLVVGDRVVV GNKRKGVLRF VGETKFASGI
WAGVELDSPQ GKNDGSVNGM EYFKCPPAHG VFALVGRVRR ILPEEEAGSD ESLKDASISQ
SSTDGSTTSS SRKSSVSQSA QATSSFRDNG GKTERTEKPD KSEKGDKGGS TSTATAAAGD
KWADKGEKQI ISTMLKKSCN WLREGMNVFV QKELGILRYI GPVHFDEGTF LGVEFRQPIG
KNDGTVGGTR YFRCRSGHGL LVRPCFVNIR GINGAKLFEQ KEPS
//
