ID A0A1V9XTM1_9ACAR Unreviewed; 558 AA.
AC A0A1V9XTM1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 28-JUN-2023, entry version 22.
DE SubName: Full=Neuropilin and tolloid protein 2-like {ECO:0000313|EMBL:OQR76854.1};
GN ORFNames=BIW11_07510 {ECO:0000313|EMBL:OQR76854.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR76854.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR76854.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR76854.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR76854.1}.
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DR EMBL; MNPL01004290; OQR76854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9XTM1; -.
DR STRING; 418985.A0A1V9XTM1; -.
DR InParanoid; A0A1V9XTM1; -.
DR OrthoDB; 3024898at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251:SF28; NEUROPILIN AND TOLLOID-LIKE, ISOFORM B; 1.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 2.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192247};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 337..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..142
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 154..276
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 455..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..511
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 293..311
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 558 AA; 61972 MW; 42FBCB7381FA00CD CRC64;
MTTAKEQKGY KFGDMDEEEK ARICFNFTVG DPERREFYSP LFNLSGGTYP NNTECIKRIT
APLNHMVRLE FRDQFHLEES PSCEFDKLEV HNGGHGYSPL AGTFCGREFP KPIQSEGREL
YLKFTSDASI EYVGFKAVYS FIPAPRTEVD PPECKFNRDG ENGRISYSDI SNGTIVHANE
TLSPIDCTWT IRVQNGSKIY ITFLHYELAQ PNNCQTNFLD IISGGAKQDR LSHFCGTIAE
PTTSVTNEVQ IRFFAQGALL KQNNKPPKLE VLYTAFREVN DPKDCNALTE FSCDDGWCIS
NKLTCDGDYN CKYRYDEDAS RCAVSSGIFL VLTSDHMIII LVVFTALVMG MCASITITCY
NKIQERRERE REYKIRRSKE VSMEIGLAPP AAPSSELEAA LAAEIRLRKQ HQTGQLAGQL
APMGGQLVDD VEDGRYLPDH PNGVLIMAGS GPVCGGGGTD GDRQSLGDRQ SVKSVPLCPQ
HGHGTYRDNA LDRDSLTPPI PPPPPPPLQA YYRMRDSPAN EMSGRWSPLE DSTMASSPQG
PSQNNGGETG RPDLVAHR
//
