ID A0A1V9Y3E1_9ACAR Unreviewed; 780 AA.
AC A0A1V9Y3E1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Transmembrane and coiled-coil domain-containing protein 4-like {ECO:0000313|EMBL:OQR80254.1};
GN ORFNames=BIW11_05185 {ECO:0000313|EMBL:OQR80254.1};
OS Tropilaelaps mercedesae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Mesostigmata; Gamasina; Dermanyssoidea; Laelapidae;
OC Tropilaelaps.
OX NCBI_TaxID=418985 {ECO:0000313|EMBL:OQR80254.1, ECO:0000313|Proteomes:UP000192247};
RN [1] {ECO:0000313|EMBL:OQR80254.1, ECO:0000313|Proteomes:UP000192247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuxi-XJTLU {ECO:0000313|EMBL:OQR80254.1};
RX PubMed=28327890; DOI=10.1093/gigascience/gix008;
RA Dong X., Armstrong S.D., Xia D., Makepeace B.L., Darby A.C., Kadowaki T.;
RT "Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae,
RT is shaped by the parasitic life history.";
RL Gigascience 6:1-17(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR80254.1}.
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DR EMBL; MNPL01000170; OQR80254.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9Y3E1; -.
DR InParanoid; A0A1V9Y3E1; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000192247; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192247};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 193..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 780 AA; 84405 MW; 8A8A9E9E1E3E2F67 CRC64;
MAGHSNLKPS VFNSAEYEKY GADALSRRLQ EPFSTRLGEA GRYSYCALVA LGLQKLFPAD
IDEPFRVASL NDFALHLNMP EQVMPVMFAL LCGEAGGSLE PYISILRDEP ALQLGFMRLI
QDLVVFAVHR GVYDARMRVF LLYTARQLEV SLALVEMYEN SVVQFLSRDN VQHSDSERRE
IAKRERNKKI KRYLMIGIAT VGGGAVLGLT GGLAAPLVAA GAGAVIGGAG AAALGSTAGI
ALISSVMGLA GAGLTGYKMK KRVGEIEEFA FDELSSGHEL HVTIGVAGWL TDDKPEAILH
PWRTMLNSRE QYVLRYETGY LVELGRAMDY LFSFAVSMAA QEALKYTVLS GLIAAVAWPA
TLVMVAGAID NPWGVCQRRS AQVGRHLAEV LLQRQHGRRP VTLIGFSLGA RVIYYCLKEL
SAREGSEGII ENAVLLGTPV PAHPEDWAPF GRIVAGNIVN GYCRGDWLLK FVYRTSSATM
KIAGLQPIAW RDRRMHNFDL SAVVNGHTDY YHKMDDILRM IGVGTLYTGS IHGDLLPIGA
LKKSITFHPN WKPQRVMEKS LRERTLEAAE NFVRPNMLRR TRSDSCLLEG TYSRLATCDG
HSGTCGKGAF SALSGLGCLR SVASGCSLSS GGPSEFSLFR TCGLSRSTSG VSDLSHTHHH
HLSSSFSGLA SVLSRLPLRH PMSLSGSVRQ SSAFPESLSA TENNSLLSLY DATSDFPGNS
PGGFVTSADG GFIEGQAEDA NTMGVGIETT PCEIVTELTN QMTAITLQST RDIAPGREPP
//
