ID A0A1V9Y8M8_9STRA Unreviewed; 726 AA.
AC A0A1V9Y8M8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Alpha-N-acetylglucosaminidase (NAGLU) {ECO:0000313|EMBL:OQR82039.1};
GN ORFNames=THRCLA_11191 {ECO:0000313|EMBL:OQR82039.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQR82039.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQR82039.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQR82039.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR82039.1}.
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DR EMBL; JNBS01004849; OQR82039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9Y8M8; -.
DR STRING; 74557.A0A1V9Y8M8; -.
DR OrthoDB; 1112009at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR007781; NAGLU.
DR InterPro; IPR024732; NAGLU_C.
DR InterPro; IPR024240; NAGLU_N.
DR InterPro; IPR024733; NAGLU_tim-barrel.
DR PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF05089; NAGLU; 1.
DR Pfam; PF12972; NAGLU_C; 1.
DR Pfam; PF12971; NAGLU_N; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT DOMAIN 17..99
FT /note="Alpha-N-acetylglucosaminidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12971"
FT DOMAIN 115..453
FT /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT /evidence="ECO:0000259|Pfam:PF05089"
FT DOMAIN 462..721
FT /note="Alpha-N-acetylglucosaminidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12972"
SQ SEQUENCE 726 AA; 83026 MW; 6C614C908E2E80D1 CRC64;
MGTAHVQLEF PVHDAIQALQ GLIRRKLGEE YIDQIELLQL KKEPQSNDMA RIDMHQGRIR
IAGTSATSMG YALHKYLKEN VHIHLDWDNH TLPLPLKLPD VSQTIVLKKT SKVTYYLNVC
TPSYSMWSWN WAHWEAHIDW MVLCGINMPL AIVGQEKLWI ETFKKFGVGE EELNEFIAGA
AFLAWGRMGN IQGSWGPFGT VPMHWIEAQS KLQLLILERM RSFGMLPALP AFAGHVPAAL
KHLYPHASMR KASQWAGFPE KYTCVYMLDP TDSLFHSIAT TFLSLQREFY GDYTSSVYQT
DMYNELLPHT SDVEYLHASA KAVIDSMLTI DPNAVWLMQG WLFYFMRTFW TDEKIKAYLD
GIPNAHMIIL DLWSDAYPIW QRTKNYFGKS WIYCVLHTFG GNLGLHGNLP QLAAEPASSL
AASDGHMVGV GLTMEGIYQN YVVYELVLDT PWTSQPIDLN PWIAQYLRHR YHICNANVKE
GWKYLLSSVY DGKDGPRCLI TYRPHWKMLH DKKMGVVDQV ILAWKCFLEA GNCNAVLKST
DTFLHDLVDI AREALSGLMA KFYAEFRTLF NHSSLTTSKE LHDKKDAILT LLFDLDKLLA
TTQAFMLGRW LADANSMAET STKAYFEYQA RNQITRWGEG ETLSDYAAKQ WSGLISGYYL
PRWECWLNAA CNAFDKKIPM DEAKVNEQIS TIEVAWQTSD EPYLNQPIGD AFDIAAALFN
KYIVNQ
//
