ID A0A1V9Y9G5_9STRA Unreviewed; 942 AA.
AC A0A1V9Y9G5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Type I inositol triphosphate receptor {ECO:0000313|EMBL:OQR82356.1};
GN ORFNames=ACHHYP_16177 {ECO:0000313|EMBL:OQR82356.1};
OS Achlya hypogyna.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Achlya.
OX NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQR82356.1, ECO:0000313|Proteomes:UP000243579};
RN [1] {ECO:0000313|EMBL:OQR82356.1, ECO:0000313|Proteomes:UP000243579}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQR82356.1,
RC ECO:0000313|Proteomes:UP000243579};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR82356.1}.
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DR EMBL; JNBR01002482; OQR82356.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9Y9G5; -.
DR STRING; 1202772.A0A1V9Y9G5; -.
DR OrthoDB; 53107at2759; -.
DR Proteomes; UP000243579; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006816; P:calcium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013662; RIH_assoc-dom.
DR InterPro; IPR015925; Ryanodine_IP3_receptor.
DR PANTHER; PTHR13715:SF99; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; 1.
DR PANTHER; PTHR13715; RYANODINE RECEPTOR AND IP3 RECEPTOR; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08454; RIH_assoc; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:OQR82356.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000243579};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 498..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 688..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 829..851
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 169..257
FT /note="RyR/IP3R Homology associated"
FT /evidence="ECO:0000259|Pfam:PF08454"
FT DOMAIN 716..858
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 942 AA; 104933 MW; 674C3C64AEF0B485 CRC64;
MASVELINRK DYTPIGGPPT GGLFHLPPPS ELAEIVTRIR ADIDHASAGI AELTRLLAAP
RLEVEALGGT KPNKNWRVSY GQERNIKLTV YAKKAWEESH LDAVKAEVAE LIVQLVAVPA
HSAATLALLY EFVAGGFGFV QNALYFACGD DPSPLMAFLS QHIEARSPTI LSVLQQLCEN
HHGQWQALMH SDTTSCLLRA VDHLVAIYDG DSRIFSVADL DTLCDILMFL SEACQGPCLS
NQDELVASRA VAVCTDMVLP RRDDRFDDAV TPSMQIRLAY HATHVILAML EGRADAGVQD
QLVARFPPLK VMGRITANYR DVQDTLAARK HHFLSPLKLL EITNFSRTSS DAVVRATPAF
KGAINLIRIV KYLLHRPPEA SANSVWSAFA AKWAELQGNA LVKEALAYFE SHMMSVEVTR
FGSIFTVHFL KPKVAKLFNP ELQERLIDAM DIGTDQALDV LVSEAATDIV DQLNVMKYLS
KNQFYKSMNR WAPGLRRTML RLCFYINFVM LLTLPIKDFS TVSMPADVLP PADKPLAQYF
ISLLGFVLLL MSLVLWVHYS FSALCFNYSK QQVSSVNKLS VASGAAIRTS FFSAFAAPFY
YLQLFIAMFV VVFYLKLESG VIKSCVAAGA AWIIYALLVA LREVSGLTRF TINSDATTVT
STYTSMITFA YNVLIDTSFT PSVMVMGTYA LCFLLGFGLS IPGLAFVIST GPWGLLFFGF
PLLDILATNE SLRFIVQAMR SNFGKLGATA IFGAVVIYIF SLIGFYFLQL EMTTDAGSQC
ATLLQCYASY IRFGLLDGGG IGDYMSSTLD HTLDYSDPMH YFQRLVYDMA FYVIIITLFL
NMIQGIIIDA FTSVREASEQ KAAMRRDRCL VCNRARNVIE LAGMEKGLLN NFARHTEREH
NLFHYFFYIQ YVLGKDDKER NGIESYVHEK LKTSDMSWIP RV
//
