ID A0A1V9YNH7_9STRA Unreviewed; 663 AA.
AC A0A1V9YNH7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Polycystin Cation Channel (PCC) Family {ECO:0000313|EMBL:OQR87273.1};
GN ORFNames=ACHHYP_09303 {ECO:0000313|EMBL:OQR87273.1};
OS Achlya hypogyna.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Achlya.
OX NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQR87273.1, ECO:0000313|Proteomes:UP000243579};
RN [1] {ECO:0000313|EMBL:OQR87273.1, ECO:0000313|Proteomes:UP000243579}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQR87273.1,
RC ECO:0000313|Proteomes:UP000243579};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR87273.1}.
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DR EMBL; JNBR01001453; OQR87273.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9YNH7; -.
DR STRING; 1202772.A0A1V9YNH7; -.
DR OrthoDB; 49832at2759; -.
DR Proteomes; UP000243579; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR013122; PKD1_2_channel.
DR PANTHER; PTHR10877:SF183; AT14535P-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243579};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 403..531
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
SQ SEQUENCE 663 AA; 74623 MW; 0248A430DF22F935 CRC64;
MKSDYFDAES PLQEGWRVSV ATAPSASISA ATIHVALKAR KQLRRHFMTL PGPLFLFFVF
IAMILTHTPI HQVYVADHGV STALNPKASD VMQSKTIVNF MKIRDIDDVP RWLNNSVLPA
VFTNSSSNGT ILPPELRGRV SAYNQLVGAV DISVFNTVQT KCQSDSPLAK RYGPCFDFDL
ELDITAAANN SERNLRRGPG SWYTLYIATA NPDVYGRLAR WQREGSAGGY YLSMATREVL
VKITTYNGQL DMFTYQVFKI EVEAGGACSP SYKVLSVPTN PYSSSSINLI LDILVGLLVL
QILGRRLWML KRQIRGQDAW SCDIGKTFIE WCSIIMVIVY YSAWFQVCNK FFASHFEDDL
AELTKFYDDL YTLPLAQQRS RMGESNQPKV SDFIDTFGPA IEFVYIVSIV TCLQLVVHVM
AAFQFHPTMN ILTNTIVSSV KRLGSFLFIF MLIVMALATS GCLLFGPQLE EFSRLDRSMV
TCINMLFGGY SYDLIKDVNE LAIVWFWVSQ SIVTLVLVNI MLAVVITSHQ EIVDVNLGKR
SFVGELALVA RDVFKIYVLR RPDLFKKLTD RMEILMHEVW TTTDVASALN ISELRAEKLI
TKLKQYAASV DVDESEHGPN AITAALEQKV GGQVLSLDHK VHDIDAKLNF LVEYIKQQQQ
RQI
//
