ID A0A1V9YPN7_9STRA Unreviewed; 618 AA.
AC A0A1V9YPN7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:OQR87736.1};
GN ORFNames=ACHHYP_08084 {ECO:0000313|EMBL:OQR87736.1};
OS Achlya hypogyna.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Achlya.
OX NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQR87736.1, ECO:0000313|Proteomes:UP000243579};
RN [1] {ECO:0000313|EMBL:OQR87736.1, ECO:0000313|Proteomes:UP000243579}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQR87736.1,
RC ECO:0000313|Proteomes:UP000243579};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR87736.1}.
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DR EMBL; JNBR01001424; OQR87736.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9YPN7; -.
DR STRING; 1202772.A0A1V9YPN7; -.
DR OrthoDB; 869at2759; -.
DR Proteomes; UP000243579; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:OQR87736.1};
KW Hydrolase {ECO:0000313|EMBL:OQR87736.1};
KW Protease {ECO:0000313|EMBL:OQR87736.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000243579}.
FT DOMAIN 33..147
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 327..544
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 556..616
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 618 AA; 66669 MW; 8E39966D3F0B9D72 CRC64;
MSPTLEKLRR AFTGLVPRAL DAELTVSAAA NLRVKALLVE SEDAHGSEYV SDRNKRRAFV
SGFTGSAGTA LVTTDKALLW TDGRYFLQAE QELSAEWTLM RQAQKDVPTV EEWLEAHLEA
GDALAIDPLL TSVATARKLV KALGNVKAGV VVCEYQKNLV DQVWADQPPQ ALSDVYALSN
EYTGASVADK LAALRTEIAK KGAGAMVLTA LDDIAWLFNI RGSDVACNPV VTAYALVTSD
AATLFMDAKE LTPALLAHFG SDVQVQGYAA IVSAIEAYAA SSTAGLVLVD PAQCNVAVFS
AIPVALRKEL PSLVMKQKAI KNEAEIEGMR QAHIRDGAAL VKFFSWLEEQ LAAGNETLTE
VSVARVQQAF REEMDKFVSL SFETISGAGP NGAIIHYDPK EETCAAVTAA HMYLNDSGAQ
YLDGTTDVTR TVHFGTPSAH EVHCFTHVLK AHIALATAVF PNECDGVKLD ALTRAPLWRA
GLDYRHGTGH GVGAFLNVHE KGVLMSFKLN PTGLLISENM IVSNEPGYYE DGQFGIRIEN
LMVAKKASGL PTTYGQFCVF ETITMCPIQR RLINTALLTA DELAWLNAYH ATVRTKLAPL
LVGAPLAYLL KETEPLSA
//
