ID   A0A1V9Z3L1_9STRA        Unreviewed;      1033 AA.
AC   A0A1V9Z3L1;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Guanylate-binding protein {ECO:0000313|EMBL:OQR92603.1};
GN   ORFNames=THRCLA_08663 {ECO:0000313|EMBL:OQR92603.1};
OS   Thraustotheca clavata.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Thraustotheca.
OX   NCBI_TaxID=74557 {ECO:0000313|EMBL:OQR92603.1, ECO:0000313|Proteomes:UP000243217};
RN   [1] {ECO:0000313|EMBL:OQR92603.1, ECO:0000313|Proteomes:UP000243217}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQR92603.1,
RC   ECO:0000313|Proteomes:UP000243217};
RX   PubMed=25527045; DOI=10.1093/gbe/evu276;
RA   Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT   "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT   identify the ancestral oomycete secretome and reveal gene acquisitions by
RT   horizontal gene transfer.";
RL   Genome Biol. Evol. 7:120-135(2014).
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. GB1/RHD3 GTPase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01052}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQR92603.1}.
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DR   EMBL; JNBS01002314; OQR92603.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V9Z3L1; -.
DR   OrthoDB; 50617at2759; -.
DR   Proteomes; UP000243217; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 1.20.1000.10; Guanylate-binding protein, C-terminal domain; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR030386; G_GB1_RHD3_dom.
DR   InterPro; IPR003191; Guanylate-bd/ATL_C.
DR   InterPro; IPR036543; Guanylate-bd_C_sf.
DR   InterPro; IPR015894; Guanylate-bd_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10751; GUANYLATE BINDING PROTEIN; 1.
DR   PANTHER; PTHR10751:SF2; GUANYLATE-BINDING FAMILY PROTEIN; 1.
DR   Pfam; PF02263; GBP; 1.
DR   Pfam; PF02841; GBP_C; 2.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF48340; Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51715; G_GB1_RHD3; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT   DOMAIN          307..514
FT                   /note="GB1/RHD3-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51715"
FT   DOMAIN          906..1013
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   1033 AA;  116343 MW;  0CB61E60D8D1ADDD CRC64;
     MNTIFTPCEP EGGPQPMYTC EVCKISMRSA KKLEDHVNHS PLHKATLQES EAAFRLELNG
     GKMDDRPISP CRQRLIYDGT KLFWRVNETL ELHIYEAINA SMITVVGQKT QARMKIQPLV
     LDLQLLYKCI AQDNEDHKQN DDEEKSQTAK REAIIKYILS RLHASKDNSE VISLHIQKQN
     TDQYDPTITN PSNRAHAIVS DTLPRRRHTY DDAKIVQKDL DVHTEALKTS RQAAEKHSEG
     IRLALDAFID LGASVKSHPR EASLSWLGAY NRVRQRHDVD VIKARMKHGH DTPFNQTPDA
     TMTMDHGFAV GGTINACTKG IWMWGEPYVL EDGTSVIFLD TEGIGSVDRE QTHDTRLFAL
     ALLLGSYFVY NSRGVIDGNA VEDLSLVVNL SKHIQTSATS QSNPGALHEF FPSFLWVVRD
     FTLQLLDNGK EITSKQYLEN ALKPQGGFSA DVAARDQIRA LLSDFFRDRD CVTLVRPVED
     EAQLRNLPNI PYGELREEFR SKFETMKKRL FEKAQPKALF GKALNGAMFT NLAKSYVEAL
     NSGKAPVISS AWSRVVQAQC EDAVDEAVEM YKKQMNTRVS DYIEGKEGFS DILEAAAEKE
     FEATANAQII NVGGGSAQFD EYGNLKRYTQ PPPMPPSDLT VSATATEEEL VAPKPVVRES
     ITLPATVDEI EEVHALCLQH AEKVLKNADI GDQPDMQAFK TTFRLATNSI LEVYKQKNAA
     ASMIYCKNLL TFLTERKFNR FHQPELSPLE YYKRTSNYLT ELDAVYEDYR RMAVGPSADA
     AYCAFMSQNI FNQAIEWTED TNKAHASALG ALQNELSTIS LQVASAQGQA TAMKELAQQD
     ILKSESSLKE AERKSKAEVD ALRASLEYKT HELEHVLNHN ATLRRLADTA QQSNFRANEV
     ATNKSPQLYA GYLIKQGRPM PNAPPGTRVK WQQRYFVLNG PALRYYNTKD DFERARSDDP
     PIDVSRAVIE EDKEVPEAFT ISFPDNSHYT LHLHAKSTYV KDEWIEQLLK VRRNVVPRGA
     PSSVSYSHGS REF
//