ID A0A1V9ZBV8_9STRA Unreviewed; 619 AA.
AC A0A1V9ZBV8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Polycystin Cation Channel (PCC) Family {ECO:0000313|EMBL:OQR95401.1};
GN ORFNames=THRCLA_07906 {ECO:0000313|EMBL:OQR95401.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQR95401.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQR95401.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQR95401.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR95401.1}.
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DR EMBL; JNBS01002115; OQR95401.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9ZBV8; -.
DR STRING; 74557.A0A1V9ZBV8; -.
DR OrthoDB; 54783at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR013122; PKD1_2_channel.
DR PANTHER; PTHR10877:SF183; AT14535P-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243217};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 381..522
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
SQ SEQUENCE 619 AA; 69043 MW; C6661D22818317CC CRC64;
MWQLPQLTTT NGKCIFGSHE LSQMSSVMTM DAKEAIKAQE YLSYEEISNA TKARYHLRRH
FGYLPIPVAF YLIFCGMALT HVPIHKMYPA ENGLYSALVT TGTDAITDTT KMKFTNIGAM
SDVFSWLNDT FIPTTFVPTD YNGNNLSSEF LHRVQLFHTI LGAVEFKTTT ASLVSCGFSG
PLSKIYPNCH DTSNLVTDYL YIDAGTPPSH AQELIQAQET SGTWLSLGTT ELDVTLTAYD
GELKIMSIIE LQLQFQLGGF IYIDSDIVAV PSNPYDGPGP IILDIFVGLF FCAALFTQVR
QWYINRKKHS SIYDYLTFWH VLEWGALISI LVFYIFWGIL CTYVYDDTLT TLLTAVGVSG
ASFNQGDNAV QARESLSQLM QRFKLMGQMM TSVRIAAMMA MLFLVARILG AMRFHPNLSV
LTSTVAKSLQ LFGPFFFVYL VCVAGFVTVG HILFGGRVLA FSTLGYTIVT VINLCFGQFS
FDSISSIDYY IALFWYWTTL IVLFLVLFNI MLAIVLKSYD EVASVSKGNR SVLSELKVVT
KDLIWGANMT KLDTSVKTGK LSKSQLFGIS EIVSELGVTE NQARRILHDA KVLSKAHEKA
VESEDLPLDV LIAKIDLRS
//
