ID A0A1V9ZC24_9STRA Unreviewed; 1103 AA.
AC A0A1V9ZC24;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein-serine/threonine phosphatase {ECO:0008006|Google:ProtNLM};
GN ORFNames=THRCLA_07784 {ECO:0000313|EMBL:OQR95534.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQR95534.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQR95534.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQR95534.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SIMILARITY: Belongs to the NPR2 family.
CC {ECO:0000256|ARBA:ARBA00008433}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR95534.1}.
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DR EMBL; JNBS01002090; OQR95534.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9ZC24; -.
DR STRING; 74557.A0A1V9ZC24; -.
DR OrthoDB; 46494at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:InterPro.
DR GO; GO:1904262; P:negative regulation of TORC1 signaling; IEA:UniProt.
DR CDD; cd17729; BRCT_CTDP1; 1.
DR CDD; cd07521; HAD_FCP1-like; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR Gene3D; 1.10.287.10; S15/NS1, RNA-binding; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR011947; FCP1_euk.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR009348; NPR2-like.
DR NCBIfam; TIGR02250; FCP1_euk; 1.
DR PANTHER; PTHR12991:SF10; GATOR COMPLEX PROTEIN NPRL2; 1.
DR PANTHER; PTHR12991; NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4; 1.
DR Pfam; PF03031; NIF; 1.
DR Pfam; PF06218; NPR2; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT DOMAIN 568..735
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT DOMAIN 772..868
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 373..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1046..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1073
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1103 AA; 124585 MW; 4F396085511AA616 CRC64;
MIQAIFYSEF DNIAGPQIVY QAPPNALSNE VFDSVSGYII IDKALCGKII TVCPQDIKIV
GYPVCIEDDK YHRNALLFNI GFVFHRTMDS TPYKPILRKL GSLMETMEKE SGFLSQESTK
SKLATILPAI LNDLTHFGEC TIPIDTANII NLKLFPKLLA PPNVHDYEVP VAIRDLKTLL
QNSAEWDLAL QKIVPFIDGV NYVKRIAITA EVDLSIVKNC MRQLLYYGCI TMIDIFLHTN
IYTTTEKISM LMNDADLQRA CVNYVAKDED NPPTFQTVFN FYCAFQPGIT VSQIWNSKTG
QQQQQQQPTQ QLQPQALLVD LRRLVTFGLI HGFLRRIHRY PIAIDRSQRA APPLSSSPSS
VNVAGLTAPN PSALVRVKTS PPQGVRDKDK VKKMMDGEHH TDEICCAFML RFSDLENILQ
SEPHLGTQLN FAWTKHLIDV MAAQVVTLSC KGDVQVDWKC SSGQLVYLDQ IVASYGTLAM
KNEGKLVAPA TGIITILPLS TTESNEKEIQ VATIELCMHP IVQNHRCVVC MRKVEQETVK
VILPQGRIME VNQAVAKELD GENIERMLKH KKLMLVLDLD HTLLHAVRTT DLVGEVDDEA
MRFYIPNIPT EHVLKLRPGL STFLSELSTL YDLHIYTHGT RSYAERITEI IDPDNTLFRH
RIVARTDTPD VGHKSLKLLF PSCDDSMIVV LDDRVDVWKE NSDNVFIIEA FHYFNTRAEI
NNASGGQVKA EVKERKPDNH LTKALRILKL VHEKFYQTTN GQLNVKYIME NMRHNVLRGC
NIVFSGVIPI DIPPENDYIW KLATSFGAKP SMTMENFPIT HLVIHPKRLG TKKYLEALKM
PNVNVVNPQW LIDCASEWMR LREDRYRIRT FAQTPKTEEE KEAGIEETKE SEIVDVTENA
QEVPKVDDVN EEETKEDSSI PPVFSSTRPP PAKGILVKQA KAKDGNKGVA FDKLPEKINA
PFTTAMRRKP LAMTHIPVPA APVRPKVVAK GVVATGGSFD FLSKMAKRAP APIVKSAPTQ
PIVPTHRIIP EPEPDIDDIF ARLEREEQNK SKKKEGENMK KNLKRKIDEP SAQARKCGKQ
TSSGICKIHK CFNSWFCRFT KRR
//
