ID A0A1V9ZCY9_9STRA Unreviewed; 1254 AA.
AC A0A1V9ZCY9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Polycystin Cation Channel (PCC) Family {ECO:0000313|EMBL:OQR95866.1};
GN ORFNames=THRCLA_07504 {ECO:0000313|EMBL:OQR95866.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQR95866.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQR95866.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQR95866.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQR95866.1}.
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DR EMBL; JNBS01002016; OQR95866.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9ZCY9; -.
DR STRING; 74557.A0A1V9ZCY9; -.
DR OrthoDB; 49832at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR013122; PKD1_2_channel.
DR PANTHER; PTHR10877:SF183; AT14535P-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243217};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 889..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..945
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1006..1026
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1038..1061
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1096..1120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 402..543
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
FT DOMAIN 1033..1123
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
SQ SEQUENCE 1254 AA; 143625 MW; E1DBAB9403F5BF4E CRC64;
MKDYNSYVEA ESPQIKLHST SPMLQESHQH QLEISEPNMP RITTEQVRLG IQGRKDIRRQ
FLNLPYPILL FGIFIAMVLT HTPIHKVYLA DHGISTVLNP KPTDILPSRA IMNFMNIRGM
QDIPQWINNS VLPAVFTKNA ANGTILPPQL QGRVSSFNQL VGAVEFSVLN SQMTDCQSDS
LLAKRYGPCF DFDSDYDIKE GNLSTRNIRR LPWYTMYIPI ANPDPYARFK RWQDEGSVGG
YYLSMATREF HVKITTYNGE LDMFSYMHFK IEVEQGGSYS PTYKVQSVPT NPYTTSSVNV
VLDALVGLLF LRILVSRLLH LKRQLFKQEP WNCEVGISLI EWCTIIMIIL YYAAWIQVCK
KFFSSHFEDQ LAQLSSFYDN LYKLPLAQQR VVMATSNQPI LSDFIDSFAP AIEFVYVVSI
VACLQLAVHV LAAFQFHPTM NILTNTIISS LKRLGSFLVI FLLVVIALAT SGCLLFGPQL
DEFSSLHKSM VTCINMLFGG YSYDLIKDIN DLAIIWFWVS QSIVTLVLVN IMLAVIIAAH
QEVVDVGLGK RSFIDEFALT VKDMIRINIF RRRDYIERFE QYLNVEPEPR EVWTAKGLEQ
ALGLTWNQAT NLIKKLKIFA NTVDAPVTKI SQISVQEARI GIKARRELRR HFINAPFPFL
LFIAFIGMVL THTPIHQVYK VDHGITTMLN PSYMDLYLAL TSINFKNIRK MDDIPKWING
TVIPSVFTYF EVDGATELPD VLKVRISSYN QLVGALEISV FNTQSAKCQS DNLLASDYGP
CFDFESKHEV TDGNLTERNT RTHPWYSVYM PYHIPNPYKR FTEWAINGTA GGYFLSMATR
EVHVKITTYN GELDIFSYIH FKIEVDEGGT FTPTYKIESV PTNPYATDSL NIALDVIVGI
FMLRIFLRRL WHLKRQMFRQ EAWTCDLRTT IIEWITLGFV ALYYLSWFSL CKKFFGTGFE
EQFAKLNDFY DELYKLPSAQ QPDYMHKSTQ PELADFIDTF APAIDFLYTV SIVACLQLVC
AVCSPIPSYA HIKRLGSFCF VFLLVVVALA TSGCLLFGPQ LEEFSSLHRA MVTCINMLFG
GYSYELIKDA NDMSLVWFWA SQTVVTLVLV NIMLAVIIAA HQEIVDNNNK NRSILDELFL
VTRDIFKHNV ICRPNRFEHL EERLQYDAEL TDMLSADQLA KVLQITERQA EKMIVKLKKY
ASTSSDWPVS TNRVSAGGQE TSRMSNEVLV QRVNDLESKM DLMIELLRRS QRQY
//
