ID   A0A1V9ZSC1_9STRA        Unreviewed;       933 AA.
AC   A0A1V9ZSC1;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Transmembrane protein {ECO:0000313|EMBL:OQS00905.1};
GN   ORFNames=ACHHYP_02157 {ECO:0000313|EMBL:OQS00905.1};
OS   Achlya hypogyna.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Achlya.
OX   NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQS00905.1, ECO:0000313|Proteomes:UP000243579};
RN   [1] {ECO:0000313|EMBL:OQS00905.1, ECO:0000313|Proteomes:UP000243579}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQS00905.1,
RC   ECO:0000313|Proteomes:UP000243579};
RX   PubMed=25527045; DOI=10.1093/gbe/evu276;
RA   Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT   "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT   identify the ancestral oomycete secretome and reveal gene acquisitions by
RT   horizontal gene transfer.";
RL   Genome Biol. Evol. 7:120-135(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQS00905.1}.
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DR   EMBL; JNBR01000020; OQS00905.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V9ZSC1; -.
DR   OrthoDB; 49329at2759; -.
DR   Proteomes; UP000243579; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR   Pfam; PF04547; Anoctamin; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243579};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        346..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..543
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        570..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        624..646
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        759..778
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        817..839
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          338..898
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          93..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          913..933
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        915..933
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   933 AA;  106067 MW;  53780130D52C14A8 CRC64;
     MADEQTRTGS PLKGRAARHR RTRSVGLPDE LEMLGVTEQA EPEAVEPERT HRRTKSFESH
     EQFLVMMQAP RSRGYTKSLK SLVKHLAPDA SQNLTASASS NRTPAASPAH LSRKKTAATK
     VWSPHHDTEA HRHLLDSSKP LEYEFALVLH NKPARARELE LHGLDKAGIE QRDVIRRCVA
     AGLEVTVLAS TVHTRKYLCL LLRPTPTRMR IERNRLAVER WLQIGAVGEV PSEIEQLIYS
     SDLGSSPCAS ARLDDDDDGG DFKFTPAERI QTIGRIITST DDLQELNPPG ANISIEDENA
     KDPIIAACFP LHNRKVNALL LAKKHSWWTK SEDITNAIRY HYGERVAFHF SFIFLYTKWL
     LIPAIVGTAL YLSLRWYSAI YYMTGLSIFG FATVTVWGTL FLKFWERENE FLNDAWNVRL
     FKEAEYPNPR FRPHGYRDIV DSNGVLLFKE PYYNPLFRLP AMMQTFFIFL LFTLTYVVGT
     TFFVQWYTAA MLAPVCAECP HCEGFLSCFD TVGATVGTWR WLYILVQGIF LGVTLDIFVY
     LLSVKLLRFF VVRENHATEA QIDRTMINRL FIINWISFFL WFMLIAFVVV PFGEPVEDWL
     SSHFHWTRIT VSWRDGRIDM STALVTPLLI TQALNLLVDT ALPNALRKRR LTAFRMARRL
     RANPADTMLA LSEAQRAASG RRSAPPLASP SLNFQTKIEL QMITPLRIPY IENDLHVSIP
     CIEGFENDKD FTTADSIVEE SQLELYDAFP DYLKMVIQFG YVVMFSVVWP FCGMAALANN
     AVHIQNCFHK LCLTRRRPVP RKANSIGQWE KTLYSTLFLG VFAVVGLVCI SSGQVEYFVG
     HCLAMDRFNG SDYSMTPEFS CFDLPSRFLV ALMLEHVGLG LVYVIMDNVS GTPASLRSSF
     QLKRELIRRA IGGQNHSHSP HSSSRSQSQF DAV
//