ID A0A1V9ZTA8_9STRA Unreviewed; 472 AA.
AC A0A1V9ZTA8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACHHYP_01608 {ECO:0000313|EMBL:OQS01237.1};
OS Achlya hypogyna.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Achlya.
OX NCBI_TaxID=1202772 {ECO:0000313|EMBL:OQS01237.1, ECO:0000313|Proteomes:UP000243579};
RN [1] {ECO:0000313|EMBL:OQS01237.1, ECO:0000313|Proteomes:UP000243579}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 48635 {ECO:0000313|EMBL:OQS01237.1,
RC ECO:0000313|Proteomes:UP000243579};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQS01237.1}.
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DR EMBL; JNBR01000012; OQS01237.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9ZTA8; -.
DR STRING; 1202772.A0A1V9ZTA8; -.
DR OrthoDB; 56015at2759; -.
DR Proteomes; UP000243579; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898:SF2; TARGET OF MYB PROTEIN 1; 1.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000243579};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 35..172
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 211..302
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 312..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 52380 MW; 7113B814D0B8148F CRC64;
MTLPLDYIQK KSALALCLPE QRTALEALDK LIDEATSDYA TAENWPLIIA VVDKLNAVLD
DEVRDEATRM VRMRLANPST TVVLAALHLV EAIVKNCGRG MRQRIAKPKF MHTMEMLYKE
HATKRGRDSL EIQARTLELV QAWGEAFLPF RRDFPGFVDT YHKMRIQGVV FPTQYDTTRA
PVLSPPRGQE DNPFAFAAEQ VEEETSVPNV YKDLGPDETF HVTKNIMDML EDMLHEASKT
HYTTLHDSDI LQELATQLKQ LDRRLMAIIE QEANRNGNHL EKYLGLNDEV QQTLGHYHEA
CAMAAKATTA LSPKRSGPLP ARKHKQEVNE AEQDELVAEG TLSPRKAPKT ATFTDDDDDD
PFAAFAKERV HKVSGPSPSK PPASVAAPLI SFDDDPIVVV PQVALAPNAV TEPALRVATK
PVAPAAQDDA PLIFWDDDVP AAAPASFNPF DSPKQAPPQP PTTTNPFDLL FD
//
