ID A0A1V9ZWZ8_9STRA Unreviewed; 742 AA.
AC A0A1V9ZWZ8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Cullin family protein {ECO:0000313|EMBL:OQS02543.1};
GN ORFNames=THRCLA_05098 {ECO:0000313|EMBL:OQS02543.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQS02543.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQS02543.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQS02543.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQS02543.1}.
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DR EMBL; JNBS01001116; OQS02543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V9ZWZ8; -.
DR STRING; 74557.A0A1V9ZWZ8; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF177; CULLIN-2; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT DOMAIN 385..606
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 742 AA; 86148 MW; 177086367F83545D CRC64;
MSLLKSKPVD FETLWSEIEP SVEVLVNGTH RPFSYEKWQG VYRGVYSICT NPGAPQAEAL
FFQLREILVR RVTEIVEILQ GESGDAEFLE LYCNHFNIYS TGSNYVSELF AYLNRYWIRY
AHSEYGQAPI PGVYPVPELA LRIWRDIVHT TMQHRVVNAL LHIFHTSRES GSEFFEYGDL
VTTTVQIYLV LGLNKQDPLK LYRNEVETIF LQDTASYYSL VAQNLLQNVS IAEYLNLVEK
LCTQEEHRCE GKMHRITVKQ VRQTCCRVLV EEHTEQICDE MNSFLENNQV DDLRRLFHLF
SELPNDQALM SLKANLKKYI EKSGMEVVQK FQHDESLKNP QEYIEALVAV REKFVDLIRE
AFGFHALMRT ALDQACRTFA NSHPRLPELL AKCTHLLMTK QGPNDNEIEV KIDQIGVVFC
LLDDKDIFKK YYAKLLSQRL IHGTSVANDF EVLLVQKLRE VCGCDFVSKL QKMFSDKLVS
QTISSSYRAW RDEHHGMDEP NYLVDFSFDV LTAGVWPIPT SFSNDNVKLP TVCQYQVDLF
TTYYVNQSTG RRLHWVHRLS HGLLRMTLSS RLYEVHASMY QIVLLLQFND QTSWSATQLH
ERTQIPNIEA VHYHLQPLVK IKLLHAAPDL TMYTLNDKFT LKRSRIKAIP VQSILDFQPP
VAGTTSSPRE VTEDRKMVLQ AAIVRVMKSR RECSFNQLFT ETTSILSNQF VPSHSFLQQN
IDLLIEKEYM RIQSDQMYMY VA
//
