ID   A0A1W0A4D7_9STRA        Unreviewed;      1374 AA.
AC   A0A1W0A4D7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN   ORFNames=THRCLA_02667 {ECO:0000313|EMBL:OQS05153.1};
OS   Thraustotheca clavata.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Thraustotheca.
OX   NCBI_TaxID=74557 {ECO:0000313|EMBL:OQS05153.1, ECO:0000313|Proteomes:UP000243217};
RN   [1] {ECO:0000313|EMBL:OQS05153.1, ECO:0000313|Proteomes:UP000243217}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQS05153.1,
RC   ECO:0000313|Proteomes:UP000243217};
RX   PubMed=25527045; DOI=10.1093/gbe/evu276;
RA   Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT   "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT   identify the ancestral oomycete secretome and reveal gene acquisitions by
RT   horizontal gene transfer.";
RL   Genome Biol. Evol. 7:120-135(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQS05153.1}.
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DR   EMBL; JNBS01000496; OQS05153.1; -; Genomic_DNA.
DR   STRING; 74557.A0A1W0A4D7; -.
DR   OrthoDB; 204547at2759; -.
DR   Proteomes; UP000243217; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   CDD; cd00171; Sec7; 1.
DR   Gene3D; 1.10.220.20; -; 1.
DR   Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR   InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR   PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   Pfam; PF12783; Sec7-like_HUS; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF48425; Sec7 domain; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT   DOMAIN          416..639
FT                   /note="SEC7"
FT                   /evidence="ECO:0000259|PROSITE:PS50190"
SQ   SEQUENCE   1374 AA;  154301 MW;  D75FAA2E1E8112CB CRC64;
     MEALRCATLS GIQTLIHIKS NQVNELAKLR GKLQQWTNPH DFEPQLVLQP FLDIIRNENT
     TGPLTRSAME AVCTILHVYD ENSALHGIPM QHALADVLDA VTQCRFQETE PNSDQYVLLT
     VVRVLDIVLQ CRAAATLTDD TIWHVVDALF AIARSNDARI SNVIRGVATD SLQRMMQVIF
     DPMEILTESS RAFGLPCAVK VLGFLCLKIQ PSSKSSEKEV LLSLQLLQTV LMKLGSHIKD
     IPSLLTYAHD ELCGAILSWL RLGSLTPGQD NIDIPLSCLS ILRLIWCYIR SCLKMQWEVM
     LQGLVPGVMD RTLALEWRVE LLQCLVDFLA DASFVIDIFV QYDCNADRSN VLELVLTTLY
     QIIQGSTDPD DFSTEIEPEM IDVALLGYWN ILNVLHQRTL MEFDMIVGPP VEASNQVLSR
     RQRKKLFQEA IAAFNVKPLT GITLLESEGF VPSPVDATSL GWTLFMKFAY MCIARVLRSL
     PPGLDKNCVG QFLGTMGKEP GPTVALTDTS TFHQQLLHAY VAAFDFQDMY LVEALRVFLS
     SFRLPGEAQQ IDRILECFSK QVFEQCRERA LFASSVDVPY LLSFSIIMLN TDLHNANIRA
     DRKMTIEDFL KNNSNYGIPG ASPLPTEYLT SIYHAIRTSP IRTCDDAEEV TSERWRDLQR
     IHAATPATER IMNSFVHTPE YDAYVLEYVA NDFLLPLLPV LSEMALFPQV LNQLVSCAQA
     AASLHCTELF GKIVAILGEQ SSLCSSHSND QAIEATVYTY CSDVVASTAT IGILQLWKSC
     SNHFDEASWA WFLSILARLR EYQLLPSSLL LERRSFLTQD ERVLYVETTQ DTALVKLQSS
     KQHAKSLSTP TSSFFSSVSR FFAMEPISAP SSPLHTPTST DSPFSSYRKL DINDLFFPST
     EDDTDVMNMV TQPWIDDFLS QCPLHFFYEH MQALSDQSIR SFFTAACSQV QRVFQPPSKT
     KLTPGTLSPG GAIFIEQIAM RVLSSELSKD IWRIVLEHAE AIIKSLDPFI RGNLHVQGMG
     YESAVYLLET LLTGLLYNGQ SQIVNILLLL ESMDMDLLAV FARPLLKGIF MDQLTLEAWS
     VWLRIVLRCS AIRSLDDYSF YCLAVLEKAS DLDNYSALVP LLTLLAHTAS VHAHSTQAIL
     TLERVLSFET SLWEASMDLH DVDKLSILGA LSSQLTHPST LTSDTLRLST LTTLRRCALE
     SPDSMLEPSS WLALLRYGLI PLTGVEIPGR SDSSNELNAA LEEFALEMPE GVDLLPTTST
     IMDMVVALFL HHLDDWMAPA AQVEFPIVWN EILFVFTTRL QMYREKKVSE EALVEQLRNV
     VHVVFALNQE EDWFIPSVQH IATLCPQIIV WKEEEPISTT IPEEQSHLVD ETQA
//