ID A0A1W0AAJ3_9STRA Unreviewed; 717 AA.
AC A0A1W0AAJ3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=Calcineurin subunit B {ECO:0000313|EMBL:OQS07218.1};
GN ORFNames=THRCLA_00785 {ECO:0000313|EMBL:OQS07218.1};
OS Thraustotheca clavata.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Thraustotheca.
OX NCBI_TaxID=74557 {ECO:0000313|EMBL:OQS07218.1, ECO:0000313|Proteomes:UP000243217};
RN [1] {ECO:0000313|EMBL:OQS07218.1, ECO:0000313|Proteomes:UP000243217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 34112 {ECO:0000313|EMBL:OQS07218.1,
RC ECO:0000313|Proteomes:UP000243217};
RX PubMed=25527045; DOI=10.1093/gbe/evu276;
RA Misner I., Blouin N., Leonard G., Richards T.A., Lane C.E.;
RT "The secreted proteins of Achlya hypogyna and Thraustotheca clavata
RT identify the ancestral oomycete secretome and reveal gene acquisitions by
RT horizontal gene transfer.";
RL Genome Biol. Evol. 7:120-135(2014).
CC -!- SIMILARITY: Belongs to the calcineurin regulatory subunit family.
CC {ECO:0000256|ARBA:ARBA00023774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQS07218.1}.
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DR EMBL; JNBS01000264; OQS07218.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W0AAJ3; -.
DR STRING; 74557.A0A1W0AAJ3; -.
DR OrthoDB; 55539at2759; -.
DR Proteomes; UP000243217; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008597; F:calcium-dependent protein serine/threonine phosphatase regulator activity; IEA:InterPro.
DR CDD; cd00030; C2; 1.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR015757; Calcineur_B.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR45942; PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1; 1.
DR PANTHER; PTHR45942:SF1; PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR PRINTS; PR00450; RECOVERIN.
DR SMART; SM00239; C2; 1.
DR SMART; SM00054; EFh; 6.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00018; EF_HAND_1; 5.
DR PROSITE; PS50222; EF_HAND_2; 6.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000243217}.
FT DOMAIN 260..376
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 442..477
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 478..513
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 562..597
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 598..629
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 630..665
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 670..705
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..272
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 72806 MW; C5639F12B26D03A5 CRC64;
MTEPPPPGRG PPPGLPPARG PPGVSAIAAP PPGRGPPPGA PPPGAARGPP PGRGPPPGAP
PPGRGPPPGA PPGRGPPPGA PPGRGPPPGG PPGRGPPPGG PRGRGPPPGA PPGGPPGGPP
GGPPRGPPPA GMPGGPPRGP PPGAPPAGGP PGGPPPGMPP GRPPPGGPPG GMPRGPPGMP
SRGPPGAPPG MPTGGPPRGP PGAPPGMPPR GPPGVPPGMM PRGQPGVPPG MMPRGPPGAP
PGMPGRGPPK GPPGAPGMRP PGMPPGPGGP PGAVPRFGKL SVKLLKGLDL VSLGALQTAD
PYAKLTIGTQ SFQTKVHEKG GNNPTWNETF EFSISTEKEL IIELFDKEQN GNDRFMGQTT
VDLIPWIAKG GFEGDIDLQD NGKSAGKVSA VVKFTKPVIG PPGAVRAPPP IGAVAPAPGA
AAVAGAPPAA PAEPPRDPNG KFSDSEILEA FKAFDLDHNN YVGAAEIRHV LINIGESPTD
EEIDEMIRMV DLDGDGQVSF DEFYKMVTGG KEPPSGLFIA SGAGDEVAAI NAGAGVASSI
QLRNERKNAL EEFANDNSIK PESVKKAYKR FQATDKDGSG QIDYTEFCEI LLVDPSPQCE
KLFQLFDNDK VGRIDVREFM ISLSNFTGAE KEEKLKFAFM IFDEDGNGVL TKQELMRILK
ANHMASNESE VARKADTIMS QGDKDGDGVI SFDEFAIVSK KFPNILFPAY TLTQQAV
//
