ID A0A1W0BLC3_9NOCA Unreviewed; 416 AA.
AC A0A1W0BLC3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Beta-ketoacyl-[acyl-carrier-protein] synthase II {ECO:0000313|EMBL:ONM48639.1};
GN ORFNames=B0T46_11390 {ECO:0000313|EMBL:ONM48639.1};
OS Nocardia donostiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1538463 {ECO:0000313|EMBL:ONM48639.1, ECO:0000313|Proteomes:UP000188836};
RN [1] {ECO:0000313|EMBL:ONM48639.1, ECO:0000313|Proteomes:UP000188836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=X1655 {ECO:0000313|EMBL:ONM48639.1,
RC ECO:0000313|Proteomes:UP000188836};
RX PubMed=26914251; DOI=10.1007/s10482-016-0667-8;
RA Ercibengoa M., Bell M., Marimon J.M., Humrighouse B., Klenk H.P.,
RA Potter G., Perez-Trallero E.;
RT "Nocardia donostiensis sp. nov., isolated from human respiratory
RT specimens.";
RL Antonie Van Leeuwenhoek 109:653-660(2016).
CC -!- PATHWAY: Lipid metabolism; mycolic acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004796}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONM48639.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MUMY01000008; ONM48639.1; -; Genomic_DNA.
DR RefSeq; WP_077116552.1; NZ_MUMY01000008.1.
DR AlphaFoldDB; A0A1W0BLC3; -.
DR STRING; 1538463.B0T36_04065; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00915; -.
DR Proteomes; UP000188836; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Reference proteome {ECO:0000313|Proteomes:UP000188836};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 11..415
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 416 AA; 43657 MW; 1C91B8E4401443BC CRC64;
MTTPSTLNGN FPNVVVTSLA ATTSIAGDVD ATWKGLLNGE SGIDVLEDSF IEEYDLPVRI
GGHLKVRPET LLSRVEIRRM AYVEQLATVL GREVWRNAGS PEVDPERLGV AIGTGLGGAD
ALIDSVDKLK NGGYRKISPL AVQMIMPNGP SAVVGLELKA RAGVVTPVSA CSSGSEAIAN
AWRMIVMGDA DMVVTGGVEG YIDMIPIAAF TMMRAMSTRN DDPKGASRPF DKDRDGFVFG
EAGALMVIET EEHAKARGAT IHARLLGAGI TSDGFHLVAP EPEGTGAARA MTRAMQTAGL
TKQDITHINA HATATPIGDT AEAKAINKAV GNHASVYAPK SALGHSIGAV GALESVLTVL
SIRDGIIPPT LNLENQDPEI DLDVVRGEAR RQEIEYAINN SFGFGGHNVA LAFGRA
//
