ID A0A1W0BNU6_9NOCA Unreviewed; 741 AA.
AC A0A1W0BNU6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Acyl-CoA dehydrogenase {ECO:0000313|EMBL:ONM47647.1};
GN ORFNames=B0T46_17310 {ECO:0000313|EMBL:ONM47647.1};
OS Nocardia donostiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1538463 {ECO:0000313|EMBL:ONM47647.1, ECO:0000313|Proteomes:UP000188836};
RN [1] {ECO:0000313|EMBL:ONM47647.1, ECO:0000313|Proteomes:UP000188836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=X1655 {ECO:0000313|EMBL:ONM47647.1,
RC ECO:0000313|Proteomes:UP000188836};
RX PubMed=26914251; DOI=10.1007/s10482-016-0667-8;
RA Ercibengoa M., Bell M., Marimon J.M., Humrighouse B., Klenk H.P.,
RA Potter G., Perez-Trallero E.;
RT "Nocardia donostiensis sp. nov., isolated from human respiratory
RT specimens.";
RL Antonie Van Leeuwenhoek 109:653-660(2016).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ONM47647.1}.
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DR EMBL; MUMY01000014; ONM47647.1; -; Genomic_DNA.
DR RefSeq; WP_077118475.1; NZ_MUMY01000014.1.
DR AlphaFoldDB; A0A1W0BNU6; -.
DR STRING; 1538463.B0T36_09990; -.
DR OrthoDB; 2431337at2; -.
DR Proteomes; UP000188836; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 2.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43292; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43292:SF4; ACYL-COA DEHYDROGENASE FADE34; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 2.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 2.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000188836}.
FT DOMAIN 6..84
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 232..349
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 392..483
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 488..582
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 594..733
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 741 AA; 77864 MW; 4D6C1B5EF732479A CRC64;
MTIATTDEHK AVQESMRGWA AAVQPIATMR ADTTGFWRTY WPTLAELGIF RVAVAEDAGG
ADGSVSDLAV LIERAAHDLV GGPVLATAVA GLVTGGSLDE TQPCGIALDT VAGPRSGGTG
DADHDNAVGS ASSLATSEPG IETTDGELLL TGTWESVLGA APQTAVLLPV RFPDGRRWCL
IPPDASGLQI EPLEPFDHST PLARVRCTDV PVAADAVFAP PYPVEDLIVA LAAAELAGIA
GWCLDTAVDY AKVREQFGRK IGSFQAVKHI CAWMLCRTEL IRAVAADAAA AVDSGGAELP
IAAAIAAAIA LDAAVDTAKD CIQVLGGIGF TWEHDAHFYL RRAVALRQLL GGAPHWRARV
TELTRAGQRR STGADRVFEE TKGTETGGGA ADEELSAQVA RIAALPTDEQ RTALAEAGLL
MPHWPKPYGR GADPMTGLVI SEELRRAGLE TPDLAIGGWA VPTLLQHGTQ EQIDRFAWAT
LRGDVVWCQL FSEPEAGSDL AALRTTATKV DGGWALRGQK VWTSLANQAD WGICLARTDP
DAPKHKGISY FLVDMRSKGI EIRPLVQITG EDRFSEVFLD EVFVPDDCVV GALGNGWRIA
RSTLSTERVA MGGNGIGPVL EELIAKLPAT GAGAELVNDR LGGFVAEAIA GLLLEQRAAV
RMLAGGDPGA QSSVRKLVGV RHRQAVAEFA VEVAGPAGAR ETEDTSEFLL TRCLSIAGGT
EQILLTVAGE RILGLPREAG S
//
