ID A0A1W0VUS6_SORBI Unreviewed; 522 AA.
AC A0A1W0VUS6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Squalene cyclase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SORBI_3010G253500 {ECO:0000313|EMBL:OQU77004.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:OQU77004.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:OQU77004.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
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DR EMBL; CM000769; OQU77004.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W0VUS6; -.
DR EnsemblPlants; OQU77004; OQU77004; SORBI_3010G253500.
DR Gramene; OQU77004; OQU77004; SORBI_3010G253500.
DR Proteomes; UP000000768; Chromosome 10.
DR ExpressionAtlas; A0A1W0VUS6; baseline and differential.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.50.10.20; -; 3.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF64; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 26..106
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 208..452
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 522 AA; 60012 MW; E8A3F237965602AE CRC64;
MWELRSFSLL QIFSLYVTGS INTIISLEHR REILRYIYNH QNEDGGWSTH VLRTSTMLGS
CLNYAALRLL GEVAHGENDA LSKGQAWILS HGSATALPQW GKIWLSDDSI AFSGWYICQW
HIFMGRNLFW PITPIVLALR EELYNIPYDN INWKEARHSC SKVLNMICCW VENQNSDAFK
KHLPRIYDYL WLAEDGMKAQ VYNGCQSWET ILTVYAFCST NLIDEFGPTI ERAHEYIKRS
QVLKDQPNYQ SYYRQRSKGS WTLSTVDSGW NSPDITAEAL KVLILLSKIS PDLVGNPIEE
QKLYDAVDCI LYSMNKGGTF SSYECQRTTS WLEILNPSEN FVNIVIDYPY VECTSSVLEA
FILFKELYPL YRTQEIDECI NNAAMFIENK QRKDGSWHGT WGICFTCGTM FAVKGLVAAG
RTYDTSSSIR KACNFLLSKQ QTTGGWGESY LSSETGVERD PIPLYQAARE LINMQLDTGD
FPQQEHIGCF NSNFYLNYAN YRNLYPIWAL GEFHHRLGAN KN
//
