ID   A0A1W1VA38_9DEIO        Unreviewed;       384 AA.
AC   A0A1W1VA38;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Leader peptidase (Prepilin peptidase) / N-methyltransferase {ECO:0000313|EMBL:SMB90289.1};
GN   ORFNames=SAMN00790413_00711 {ECO:0000313|EMBL:SMB90289.1};
OS   Deinococcus hopiensis KR-140.
OC   Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=695939 {ECO:0000313|EMBL:SMB90289.1, ECO:0000313|Proteomes:UP000192582};
RN   [1] {ECO:0000313|EMBL:SMB90289.1, ECO:0000313|Proteomes:UP000192582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KR-140 {ECO:0000313|EMBL:SMB90289.1,
RC   ECO:0000313|Proteomes:UP000192582};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the peptidase A24 family.
CC       {ECO:0000256|ARBA:ARBA00005801}.
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DR   EMBL; FWWU01000009; SMB90289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W1VA38; -.
DR   STRING; 695939.SAMN00790413_00711; -.
DR   OrthoDB; 9789291at2; -.
DR   Proteomes; UP000192582; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1220; -; 1.
DR   InterPro; IPR000045; Prepilin_IV_endopep_pep.
DR   InterPro; IPR010627; Prepilin_pept_A24_N.
DR   PANTHER; PTHR30487:SF0; PREPILIN LEADER PEPTIDASE_N-METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR30487; TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME; 1.
DR   Pfam; PF06750; A24_N_bact; 1.
DR   Pfam; PF01478; Peptidase_A24; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Methyltransferase {ECO:0000313|EMBL:SMB90289.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192582};
KW   Transferase {ECO:0000313|EMBL:SMB90289.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        87..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        356..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          13..94
FT                   /note="Prepilin peptidase A24 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06750"
FT   DOMAIN          109..227
FT                   /note="Prepilin type IV endopeptidase peptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01478"
FT   DOMAIN          237..343
FT                   /note="Prepilin type IV endopeptidase peptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01478"
SQ   SEQUENCE   384 AA;  40736 MW;  647FC4F6D8913E80 CRC64;
     MSLDVLFVVF AAVLGLLVGS FSNVLIWRLP RGENIAFPPS HCPHCNHQLG VLDLVPVFSW
     LALRGKCRYC GAPIKPRYPT VELLTGLGYA VIAALFPFAV FGWGTLGLMV LFTLLLVGSA
     IDLDTYTLPD ELTLPGVALG LLFALLNTRS GTAQGVLPSF SEAVQGALMG AGLLVTINLL
     GSWVMRRLRE RQYPELPIGY QQISLGLLAG AWLGPWWGLG VAMLSVAANL AARRVVRVPE
     LLTLGGCLVS LTLGSSGFGP GLILMLQGAL GGAGAVSLVA GVYWWIQYRR EAEAEGSDDE
     HGDPVAMGFG DVKLAAVIGA FLGWERLLVA VVVAVFAGAI LGLAQLAMKR ENRIKFGPYL
     ALGALVALIW GRSLVDAYKG MLGL
//