ID A0A1W1VBN8_DESTI Unreviewed; 760 AA.
AC A0A1W1VBN8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:SMB90819.1};
GN ORFNames=SAMN00017405_1366 {ECO:0000313|EMBL:SMB90819.1};
OS Desulfonispora thiosulfatigenes DSM 11270.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulfonispora.
OX NCBI_TaxID=656914 {ECO:0000313|EMBL:SMB90819.1, ECO:0000313|Proteomes:UP000192731};
RN [1] {ECO:0000313|EMBL:SMB90819.1, ECO:0000313|Proteomes:UP000192731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11270 {ECO:0000313|EMBL:SMB90819.1,
RC ECO:0000313|Proteomes:UP000192731};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FWWT01000017; SMB90819.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1VBN8; -.
DR STRING; 656914.SAMN00017405_1366; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000192731; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192731};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 519..712
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 760 AA; 85523 MW; 582A2EEFD5092520 CRC64;
MNVERKIVNF TLVYIVGIIV GFNNLYLACT LIFCGICLSL GMVKIHKNYL KVIFILLPLI
LGIVIVNLHN IVDESLAPWE GENVEVTGKI KPKILSNNRY IIELEKINKT KLKNKPLVLI
QFKKDCPEYF SWNDKVKLKG KLNGLKVATN PGQFSEKDYW SKQKVYQKIY VLEKGEVLKQ
GTGFFAYTFK FREKVAKKIV DLFPEKQSGI ILGIILGDKS NLDEHYYDLF QKLGIVHIFA
VSGLHVGYIL GAYLLLSKVC KISPTFNLFF AIILLFFYSL ITGLSPSVIR ASLMSILVLL
GTNLLKYKDF YTIIASSALV ILIFNPLALF TISFQLSFIT VWGLVYFSQI TREIFVRFPS
KIREILSISL AAQIASLPIV VYYFNLISFV APLVNVLIVG IVSVLVPLLL ATILISFGST
LVVSPLIFFC NVLLDGIMLF SDLIMKIFSS GYTFFPSPPL IGIILYYFIL ILIRERKTIY
PYIPKKIRII TSIILVVILL LLTIPINQEI RMTFLDVGQG DSCVIQTNQN KKIVIDGGPD
TTTLFNYLKH IGTNKVDLVV LSHPDSDHIN GLFKVLESIK VSTLLVPPDA YNNEALQELK
NIAKKKETKI IEGKQGMKLT VGGQIILKII APHPNNLSAL DVNNASIVFI FTYGKQDILF
TGDVENKGIE KFVNQLDEVE VIKVPHHGSK SSDSAELYDN TNPSMAIISA GRSNQYNHPH
QDIVKKLKKR KIETFRTDKN GAIILKVKKD RLKPTTTLVN
//
