ID A0A1W1W4Q1_9BACT Unreviewed; 337 AA.
AC A0A1W1W4Q1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=O-methyltransferase family 2 {ECO:0000313|EMBL:SMC00585.1};
GN ORFNames=SAMN00120144_4128 {ECO:0000313|EMBL:SMC00585.1};
OS Hymenobacter roseosalivarius DSM 11622.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=645990 {ECO:0000313|EMBL:SMC00585.1, ECO:0000313|Proteomes:UP000192266};
RN [1] {ECO:0000313|EMBL:SMC00585.1, ECO:0000313|Proteomes:UP000192266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11622 {ECO:0000313|EMBL:SMC00585.1,
RC ECO:0000313|Proteomes:UP000192266};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FWWW01000105; SMC00585.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1W4Q1; -.
DR STRING; 645990.SAMN00120144_4128; -.
DR OrthoDB; 9766840at2; -.
DR Proteomes; UP000192266; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.1350; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:SMC00585.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000192266};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:SMC00585.1}.
FT DOMAIN 10..88
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 111..317
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 247
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 337 AA; 37132 MW; A3D47F51975CB383 CRC64;
MAQELPPAIQ LMQVMFGFAA SRALGVAAEL GIADLLKDGP KSAGELSRRT NTHERSLYRV
LRACASVGVF SEDDDTRFRL TPLAEPLLSD VPGSLRPFVT LMTNDFQYQT WAELLYSVQT
GEPAFDKVFG TSSFDYFWRN EKAGKVFNDA MSSNSAFSSA AVLEAYDFSG ISTLVDVGGG
HGFLLASILN KYPKLRGILY DMPAIVEAAE DLLTSHGVAD RCERVGGNFF GLVPAGADAY
VMKHIIHDWN DEQSLTILKN CREAMNPNGK VLVVEMVLPE GNESSFGKFL DLQMLLYLRG
CERTEAEYHQ LFDQAGLELT RTLPTTSPFS IIEGIRK
//
