ID A0A1W1X4F6_9CLOT Unreviewed; 424 AA.
AC A0A1W1X4F6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Radical SAM superfamily enzyme YgiQ, UPF0313 family {ECO:0000313|EMBL:SMC18720.1};
GN ORFNames=SAMN02745134_00644 {ECO:0000313|EMBL:SMC18720.1};
OS Clostridium acidisoli DSM 12555.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121291 {ECO:0000313|EMBL:SMC18720.1, ECO:0000313|Proteomes:UP000192468};
RN [1] {ECO:0000313|EMBL:SMC18720.1, ECO:0000313|Proteomes:UP000192468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12555 {ECO:0000313|EMBL:SMC18720.1,
RC ECO:0000313|Proteomes:UP000192468};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FWXH01000002; SMC18720.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1X4F6; -.
DR STRING; 1121291.SAMN02745134_00644; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000192468; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR025274; DUF4070.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13282; DUF4070; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000192468}.
FT DOMAIN 1..131
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 153..377
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 424 AA; 49117 MW; F923E8F983A923D1 CRC64;
MNLLLITASS DEIRNIRKSR VIGFQQCTMP YLAALTPPNW NIEHVDEEVE RVNFNKHYDL
VAITFHTPSA NHAYNIATRF REKGVVVAMG GPHVTLMPQE AEKYADVIFV GESEITWPQF
IYEFEKKQYK RKYICTYPPE LDGIPMSRKD LFHRKDHSNG IMFATRGCPN KCEFCTISVM
YKNKLRKRPI EEAAREYASF KGKVIIFWDD NISADLEYSK KLFKAIAPYK KWWSSQASIN
AGKDDEFLEL AAKSGCKQLF LGIESISQKS LNSANKSFNK VDDFYKVIHK IHSYGISVQA
GVVFGFDQDT KNIFKDTLDF LENAGVQNAT FNILTPYPGT PLFNRLEAEN RILTYDWSKY
NSRKDVVYIP KNMSSEELLE GFIWANKRFY SLKSISKRLS KSTAGLYWTL PLNLMYHYYL
KLHK
//
