ID A0A1W1X4P4_9CLOT Unreviewed; 686 AA.
AC A0A1W1X4P4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=SAMN02745134_00708 {ECO:0000313|EMBL:SMC18924.1};
OS Clostridium acidisoli DSM 12555.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121291 {ECO:0000313|EMBL:SMC18924.1, ECO:0000313|Proteomes:UP000192468};
RN [1] {ECO:0000313|EMBL:SMC18924.1, ECO:0000313|Proteomes:UP000192468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12555 {ECO:0000313|EMBL:SMC18924.1,
RC ECO:0000313|Proteomes:UP000192468};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FWXH01000002; SMC18924.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1X4P4; -.
DR STRING; 1121291.SAMN02745134_00708; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000192468; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192468};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 466..624
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
FT REGION 54..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 78261 MW; 107EC6915B78E706 CRC64;
MKIINVLHNK TTKKVFIFAS VFIIIYGIML TSIVPKTYNL KEGEIAKNDI KAQRDVEDKT
ATEEREKEAS DSVGQQYDKK VEVESESEQD LNNDFEKFNA IKNQNIDINQ KITSLKTTLA
YNLSDSQANT WLTISNDDNT SLQNYIIKTI KGIYSNDIRE ENSYDIKNAQ NYINNQFAKS
KFNKDVIELG TIIAQYYIKP NLFINQDKTN EMKDNAKKKV AQVIIKKDQI IVKEGEPITK
EELDILADLG LLNNNKNSNW YVYVSLGALD FIILFIEMYY LYKYHRELFE TNSNLILIFL
LNIVFLILAR TINIISPFLI PLAFLPMLYT ILLNDRVALF MSLFNCILMS IVVEFNVQLI
LIAIMSTLIS SMVLKKMQMR NDILYASIYI ALVNSILTFS IGFLVSNNFL NILTITVFSF
LGACFSAILT IGFLPILESV FDIVTPVKLL ELSNPNQPLL KKLLVEAPGT YHHSIMVANL
AEAATEEVGG NQVLARVASY YHDVGKVRRP YFFKENQFGK ENPHDKMTPN LSALVVISHI
KDGLELAEEY KLPKVIQNII SEHHGTTLAK YFYITMKNSC DNPEEIKEEN FRYPGPIPSS
KESAIIMLAD SIEAAVRSIN EPTKGKIEEM VNNIIEARLN EGQLDNCDIT FKDLSKIREA
FLNSLNGIYH QRIEYPTDKS QISKEK
//
