ID A0A1W1XE78_9NEIS Unreviewed; 588 AA.
AC A0A1W1XE78;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=SAMN02745857_01351 {ECO:0000313|EMBL:SMC22180.1};
OS Andreprevotia lacus DSM 23236.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chitinibacteraceae; Andreprevotia.
OX NCBI_TaxID=1121001 {ECO:0000313|EMBL:SMC22180.1, ECO:0000313|Proteomes:UP000192761};
RN [1] {ECO:0000313|EMBL:SMC22180.1, ECO:0000313|Proteomes:UP000192761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23236 {ECO:0000313|EMBL:SMC22180.1,
RC ECO:0000313|Proteomes:UP000192761};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FWXD01000006; SMC22180.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1XE78; -.
DR STRING; 1121001.SAMN02745857_01351; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000192761; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192761};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 308..361
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 436..568
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 563..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 63921 MW; 98F66569727EB620 CRC64;
MRLDLRTALG AAFAIVAALI VLTLSSVLER LSAEMVTADI DRSLYALSDR MHDELTNGLE
ARLRDVSVIA QIKQIRDPAT PAEDNRAILQ QLKQNYAEYA WIGMADPQGK VHYAADHLLD
GADVSARPWF KAGLKGPFIG DVHEAKLLAK LLPPPASGEP LRFLDVSYPI YDLQGKLSGV
IGAHLSFEWA RSVEQKIFGP MSQHGVQAFM LAANGKVILA PNGLEGVALP ELKGPIHSSV
LRWPDGKEYL TSLLQTRSDG PAQLGWQILV RQPADRAFES VRNLRTSILW VGLACTLLFA
VIGAVLAGVI AHPLRKLSRS ADRLRAGEHN AAIPAGAIYR EANQLSLSLK QLVDSLSLKT
LQLAELNNTL EAQVVERTAS LDASNEHLLT TLRERSELVQ QLEKLANTDA LTGALNRRAF
YERADHELRR AARGAAPLCV IAIDIDFFKR INDQEGHDIG DEVLRRMAST CQQTLRDVDL
FARFGGEEFI ALLPDTAIDG ALVVAERLRE AVADIRVVLP AHVLQLTASF GVAELGNGEA
LAAMLSRADK ALYEAKHGGR NRVCTPPPLS SQLPQAGENS SATAPTKD
//
