ID A0A1W1XV18_9NEIS Unreviewed; 680 AA.
AC A0A1W1XV18;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN02745857_02948 {ECO:0000313|EMBL:SMC27702.1};
OS Andreprevotia lacus DSM 23236.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chitinibacteraceae; Andreprevotia.
OX NCBI_TaxID=1121001 {ECO:0000313|EMBL:SMC27702.1, ECO:0000313|Proteomes:UP000192761};
RN [1] {ECO:0000313|EMBL:SMC27702.1, ECO:0000313|Proteomes:UP000192761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23236 {ECO:0000313|EMBL:SMC27702.1,
RC ECO:0000313|Proteomes:UP000192761};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FWXD01000018; SMC27702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1XV18; -.
DR STRING; 1121001.SAMN02745857_02948; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000192761; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SMC27702.1};
KW Cilium {ECO:0000313|EMBL:SMC27702.1};
KW Flagellum {ECO:0000313|EMBL:SMC27702.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000192761};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 109..128
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 280..313
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 680 AA; 73640 MW; 7D0B919BFC47EFD6 CRC64;
MNALRRVFQQ NTDIAIVLLV MGVLVVLFTP IPAGLLDVLI LANFSFALLI LLLTFYMPKP
VEFSTFPSLL LIATLFRLSL NVAATRLILG HGDAGRVIGA VGGYVIGGNY AIGLIVFLIL
IVVQYVVVTN GAQRVSEVAA RFTLDSMPGQ QMSIDADLNM GFIDQEEAKR RRKNLEKEAG
FYGAMDGASK FVKGDAIAGI IIMLINIIGG LVIGVMQMGM PLADAMRTFT LLTIGDGIVT
QVPALVISVG TGLIVTRSAS DAHLGKEVIR QLGAFPKTLL LVSGALGVLL FLPGIPALPA
AGLSLGFFAM AWWSRRLQNE PAAADAQDDA DAASDEEDAY GELDIEPVEV YIAPSLGSLL
GESQLVLMER IGVFRKQYAS ESGLVLPKVK IREAARMPQD GYEIAIYGAV AARSELMPAH
TLAIRANPNA RKLNGVETKD PSYGLPAVWI EDSEKDAARA GKYTLVDPAT VFLTHLCEVL
RQQSAALLTR AETDRLLNRL RQQQAGLVEE IVPTLLSVGD IHRVLQNLLR EKVSIRALQA
ILETLGEAAK ASKDINYLTE MARQRLGPII CQALANNQNV LQVLTLDPAV EQRLLQGIHP
GENGVAGIDP QTTEKMLRQL AQQVEKMMKS NLMPVLLCTP ELRRQLRMLS ERMMPHLRVI
ALTEVPNTVE LRAFGSVAAG
//
