ID A0A1W1Y4H6_9LACT Unreviewed; 435 AA.
AC A0A1W1Y4H6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Serine protease Do {ECO:0000313|EMBL:SMC31024.1};
GN ORFNames=SAMN04487984_0344 {ECO:0000313|EMBL:SMC31024.1};
OS Aerococcus suis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Aerococcus.
OX NCBI_TaxID=371602 {ECO:0000313|EMBL:SMC31024.1, ECO:0000313|Proteomes:UP000243884};
RN [1] {ECO:0000313|Proteomes:UP000243884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21500 {ECO:0000313|Proteomes:UP000243884};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; FWXK01000001; SMC31024.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W1Y4H6; -.
DR STRING; 371602.SAMN04487984_0344; -.
DR Proteomes; UP000243884; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022825};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SMC31024.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000243884};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..401
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 46453 MW; AB58BE8DE37110A7 CRC64;
MYTDNQEEKI PKNPNEPHKP EPKKNHKPWI PAIVGGLIGA SLVGTVGAVV DHNDGDSVSQ
EQVEKIVQER VQEEADKHKD GNKQQASLDV STDVTETTAK TQDAVVSVAN LANKKSTIDL
FGFVQPDQKS SDGNSSEDDY ETASEGSGVV YKKDGQYAYI VTNNHVIDGS DALEVLLNNG
DQVKAELVGT DVWTDLAVLR IPASAVDTVA EFGDSDSLKV GEQAIAIGSP LGSEFASTVT
QGIISGLNRN VPVDLDGDKT MDWQVNAIQT DAAINPGNSG GALLNSAGQV IGINSMKISS
GQVEGMGFAI PSNDVKTIID QLEAKGHVER PQLGVAMANL NQIPIEQQDE VLKAPDNLEN
GVVVVDIDSD SPAAKSDLKV NDIITSFNGH EVTDNVSLRK ALYDAKPNER VNVEVYRNGK
KQTVTIQLEP QSENP
//
