ID   A0A1W1Z2C3_9FIRM        Unreviewed;       632 AA.
AC   A0A1W1Z2C3;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SMC42536.1};
GN   ORFNames=SAMN06297397_0867 {ECO:0000313|EMBL:SMC42536.1};
OS   Clostridiales bacterium.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales.
OX   NCBI_TaxID=1898207 {ECO:0000313|EMBL:SMC42536.1, ECO:0000313|Proteomes:UP000192328};
RN   [1] {ECO:0000313|Proteomes:UP000192328}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WTE2008 {ECO:0000313|Proteomes:UP000192328};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:SMC42536.1}.
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DR   EMBL; FWXZ01000001; SMC42536.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W1Z2C3; -.
DR   Proteomes; UP000192328; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          302..582
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   632 AA;  71427 MW;  E559CDF9600A7073 CRC64;
     MTLNQKQSRW KLFLFDLAFY LLVGIFIFIV YPSTIDRLNT TEQLLYIALG AVCVFVLRFV
     FNVYKRIWRY AGSSDYLWLV VADFIAGVIF VLLRAPLMPQ GITFVRAVSL ICLNLLGAIC
     MRLTYQFAYQ NRNQTSKGQR RILSFLQFIT GVKFAQDEAL PENRKIRVAI IGAGSVGAML
     ADELLNNPKA VYKPVCFVDA NKEKVGRTIA RVPVVNNETD LNSFGVQEVV FALPNITNER
     RKELFEVYKN KGYKIKVYDY PSLENTDGRR QLRDFAIEDL LYRNTVDVID EKTAAWYRGK
     NVMITGGGGS IGSELARQIA KIGPGRLTLL DNYENGVYDI QQELLTRYPG LNLKVEIVNI
     CDADGIQRVL CINTPDIVLH AAAHKHVPLM ERNVMEAVKN NVFGTLNMVE ACERNGVKRF
     IMISTDKAVN PTNVMGATKR MCEMIVQSRK GDRTSFSATR FGNVLGSNGS VIPLFRRQIA
     NGGPVTITDK RITRFFMTIP EASQLVMTSG AMAKNGELYV LDMGKPVKIY DLAEEMIRLS
     GLEPYKDIDI VETGLRPGEK LYEELLIRTE EMDKTENDLI FIERDKPLSE EEIWEKLNIL
     REALATGHNT AVKEALMKVV PTYHTPEEVN GK
//