ID   A0A1W2A7D7_9SPHI        Unreviewed;       366 AA.
AC   A0A1W2A7D7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Thiol-disulfide isomerase or thioredoxin {ECO:0000313|EMBL:SMC56546.1};
GN   ORFNames=SAMN04488524_1222 {ECO:0000313|EMBL:SMC56546.1};
OS   Pedobacter africanus.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=151894 {ECO:0000313|EMBL:SMC56546.1, ECO:0000313|Proteomes:UP000192756};
RN   [1] {ECO:0000313|Proteomes:UP000192756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12126 {ECO:0000313|Proteomes:UP000192756};
RA   Varghese N., Submissions S.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWXT01000001; SMC56546.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2A7D7; -.
DR   STRING; 151894.SAMN04488524_1222; -.
DR   OrthoDB; 1069091at2; -.
DR   Proteomes; UP000192756; Unassembled WGS sequence.
DR   GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd02966; TlpA_like_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR000866; AhpC/TSA.
DR   InterPro; IPR025380; DUF4369.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR42852; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   PANTHER; PTHR42852:SF6; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   Pfam; PF00578; AhpC-TSA; 1.
DR   Pfam; PF14289; DUF4369; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SMC56546.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192756};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..366
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012461528"
FT   DOMAIN          224..365
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   366 AA;  40610 MW;  89B3B008AFE5517D CRC64;
     MRKLKYLAAA MLLAMASSGS FAQKDGSYTL TGTVKGIADG TVELATYDSR TRTTKKIGSA
     SVKNGKFVVS GKLNTPELVS LSFIPGNWGA QVFLENRAIA ITADTTGSQH YDYTQYGGVK
     GAVLKKVQVN GSASHTAYQG YEASITGLKG REALFSAQLN YIRPYIAKHP GSVAGAYMLS
     NHYMFNSSLP LNEMEQMLAQ FKAPATQSLY YSNLQKEVAE RKAVLPGNYA EDFTLMKPDS
     TKFTLSSTRG KYVMIDFWAS WCKPCREAIP HWKEVYAKYK NRGFEIVAVT NDSRWSDWKK
     AMDAEQMPWI QLADEFPVKN MPARVISKYK HGTIPLYVLL DKEGKILVKS GDKSEIDRKL
     AELLGS
//