ID A0A1W2AQN3_9FIRM Unreviewed; 635 AA.
AC A0A1W2AQN3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=MutS domain V {ECO:0000313|EMBL:SMC63016.1};
GN ORFNames=SAMN06297397_1660 {ECO:0000313|EMBL:SMC63016.1};
OS Clostridiales bacterium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1898207 {ECO:0000313|EMBL:SMC63016.1, ECO:0000313|Proteomes:UP000192328};
RN [1] {ECO:0000313|Proteomes:UP000192328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WTE2008 {ECO:0000313|Proteomes:UP000192328};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:SMC63016.1}.
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DR EMBL; FWXZ01000003; SMC63016.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2AQN3; -.
DR OrthoDB; 9808166at2; -.
DR Proteomes; UP000192328; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF14; DNA MISMATCH REPAIR PROTEIN MUTS, TYPE 2; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 403..419
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 635 AA; 70834 MW; 844196EBEDB21E8B CRC64;
MTQDMITLGF DLIIEQLQNQ AVSQAARRKL AETEPILHEG LCRARMEETT AALYVMENTG
TPPISETDGT ETGLIQAAQG GMLLPSQLCS VARFCATIQR LRRYLQNAQT WSAGIASWQT
ELPDLTGLED DIERSVREDT VLDDASPALR NLRRQREFTE QSIREKLNQI LFHHKKELAD
SYITQRNGIF VIPVQKRFQG SFPGHAVDTS AKGNTVFMEP TAVQALRQEL EMLLIEIDTE
ERRILWELSD RVAAEETPLR DAIRVMTDLD ILFARAKLSM EMKARPVELT AERRIRLVNA
RHPLLDPDTC VPLNLELALP DSGIAVTGPN TGGKTVCLKT VGLLTLMAQS GLHIPCGEGT
VIGLMDRVLC DIGDSQSISQ NLSTFSGHMT NVIRILEECS RESLVLLDEL GSGTDPAEGS
GLAAAILEEL LRRGCFFLVT THDPQIKQWA EQTEHVVSAR MAFDRESLMP LYRLELGKSG
KSCAIEIARR LGMDEGLLSR ARQVADQGPD TVPEPGRKPM RIPAGRLQRL REKADGDFER
FTMGDSVLLL PDKKNAIVYQ PADDDGNVII QFQGKKITVR HNRLKLLVPA AQLYPPDYDF
SIIFDTVANR KAAHTMDRKF DRDAVIIHKE GNKEI
//
