ID A0A1W2AZ44_9FIRM Unreviewed; 688 AA.
AC A0A1W2AZ44;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN04488500_106212 {ECO:0000313|EMBL:SMC65742.1};
OS Sporomusa malonica.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=112901 {ECO:0000313|EMBL:SMC65742.1, ECO:0000313|Proteomes:UP000192738};
RN [1] {ECO:0000313|EMBL:SMC65742.1, ECO:0000313|Proteomes:UP000192738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5090 {ECO:0000313|EMBL:SMC65742.1,
RC ECO:0000313|Proteomes:UP000192738};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Cell membrane
CC {ECO:0000256|RuleBase:RU364093}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FWXI01000006; SMC65742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2AZ44; -.
DR STRING; 112901.SAMN04488500_106212; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000192738; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR InterPro; IPR006302; T3SS_HrcV.
DR NCBIfam; TIGR01398; FlhA; 1.
DR NCBIfam; TIGR01399; hrcV; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SMC65742.1};
KW Cilium {ECO:0000313|EMBL:SMC65742.1};
KW Flagellum {ECO:0000313|EMBL:SMC65742.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000192738};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 67..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 104..131
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 688 AA; 75629 MW; 6D4166A8772DFF2D CRC64;
MATQQSRLFA GLEKYSDIMI SVAIITIVVM MIIPLPTILL DLLLTLNITL ALIIVMVAVY
NIEPLEFSVF PSLLLITTLF RLALNVSSTR LILLDGHAGE VIAAFGNFVV GGNAVVGFIV
FVILIIIQFI VITKGAERVA EVAARFTLDA MPGKQMSIDA DLNAGLITDK EARDRRKNIQ
READFYGAMD GASKFVKGDA IAAIIIIIIN IVGGFIIGML QRNMDVLQAL QTYTLLTVGE
GLVNQIPALL ISTATGIVVT RAASEANLGK DLTRQIINNP RIFFIASGVL CLLGIIPGLP
GFPFFLLSLI TGGIGYLLIR TQQSEVQMEM SQQEEKEKEE VRKPENIVSL LQVDPMELEI
GYSLIPLVDV SQGGDLLDRV VMIRRQCALE LGLIVPTIRI RDNIQLKPNI YVIKLKGIEI
ARGELMLDHF LAMDSGAAFE PVPGIETVEP AFGLPALWIQ ESYREQAELA GYTVVDPVSV
LATHLTEIIK SHAAEILGRQ EVQTLIESVK QNNSAVVDEL TPNLLSLGEI QKVLSNLLRE
KISIRDLVTI FETLADYAQL TKDTEVLTEY VRHALARQIS KQFVNNNILT CLTIDPQLEN
TVINAVQRTE QGSYVALEPQ RVQAIISSLT NELPKLTNMG YQPVVLTSPG ARLYFRKLTE
RVAPNLTILS YAELDAKIEV QALGMVRL
//
