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Database: UniProt
Entry: A0A1W2BJ62_9DELT
LinkDB: A0A1W2BJ62_9DELT
Original site: A0A1W2BJ62_9DELT 
ID   A0A1W2BJ62_9DELT        Unreviewed;       898 AA.
AC   A0A1W2BJ62;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   11-DEC-2019, entry version 11.
DE   RecName: Full=ATP-dependent RecD-like DNA helicase {ECO:0000256|HAMAP-Rule:MF_01488};
DE            EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_01488};
GN   Name=recD2 {ECO:0000256|HAMAP-Rule:MF_01488};
GN   ORFNames=SAMN02746065_108133 {ECO:0000313|EMBL:SMC72916.1};
OS   Desulfobacterium vacuolatum DSM 3385.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfobacteraceae; Desulfobacterium.
OX   NCBI_TaxID=1121400 {ECO:0000313|EMBL:SMC72916.1, ECO:0000313|Proteomes:UP000192418};
RN   [1] {ECO:0000313|EMBL:SMC72916.1, ECO:0000313|Proteomes:UP000192418}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 3385 {ECO:0000313|EMBL:SMC72916.1,
RC   ECO:0000313|Proteomes:UP000192418};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase.
CC       Has no activity on blunt DNA or DNA with 3'-overhangs, requires at
CC       least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000256|HAMAP-
CC       Rule:MF_01488}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01488};
CC   -!- SIMILARITY: Belongs to the RecD family. RecD-like subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01488}.
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DR   EMBL; FWXY01000008; SMC72916.1; -; Genomic_DNA.
DR   BioCyc; GCF_900176365:B9A32_RS09335-MONOMER; -.
DR   Proteomes; UP000192418; Unassembled WGS sequence.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01488; RecD_like; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR006345; DNA_helicase_RecD-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029493; RecD-like_HHH.
DR   InterPro; IPR041451; RecD-like_SH13.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   Pfam; PF14490; HHH_4; 1.
DR   Pfam; PF18335; SH3_13; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_01488, ECO:0000313|EMBL:SMC72916.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01488};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192418}.
FT   DOMAIN          350..496
FT                   /note="AAA"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   NP_BIND         361..365
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01488"
SQ   SEQUENCE   898 AA;  100570 MW;  4DEC190EF68AE7F9 CRC64;
     MVTPLSHNGV IREHLEGIVD RVTFHNPDNG WSILRVTPFN AMGQETVVVH QTRVFAGATM
     RFQGAWTVHP KFGRQFQAVV ATEKKPATQA ALEKYLGSGL IKGVGPKTAR KIVKHFQKET
     LTIFETDMER LTEVPGIALK KLEMIRHAWT RHKSIREVMM FLQTHGISTL FAVRIYKTYG
     DKAITNVTQD PYRLANDFYG IGFFSADKVA LSIGLDRQSP QRIMAGIRHV VAAGRNEGHC
     YLTHSQIDEK VTALLELDLK DQLSSLLDHM VKERQLMVRE LPTEKNSTIR CYYVRSLYFD
     ERYVAKRLAG MGPPPQVDRE RVQRWIKLFS KSREINLSDE QALAVAQVVG EKFSILTGGP
     GCGKTTTTQV IVKLAQAMGL RVLLAAPTGR AAQRMGEVIG QEAKTIHRLL EWKGGEFKKN
     ESQPLDTDFL IVDECSMLDI SLTASLLKAV PQDSRVLFIG DADQLPSVGA GNVLRDIISA
     DTVPCFRLTQ IFRQARSSKI IQYAHQINRG EMPWVISPFK KPSVWQDGSD CLFMDSDEAT
     GEQIRFIERV KRLCHGALEG SQSVSAAGTC ENIKSHLKIS RENDGCDDGC DDGSRDGDGG
     NGNGNGNGNG NGNGNKDTYA NGIVNKKENK KDALLYEFRV NETVRPYETE ITIPAKFQHV
     NLTALTQADT RVAELTAVLK KVHPWSSLHY GFAALDVVKK LYLEWIPKYF GPDREIQILS
     PMTRGTLGTA NLNGVIQNAA NPFMEGKPQL KVGERIFRVG DRVIHRRNNY DLGVFNGDIG
     TIVAIDNSEP TLTVAFYPDR RQVFYQRDDI MELDLAWAIT IHKSQGSEFE VVIIPVLTQH
     YKMLFRNLLY TGLTRAKKLA VFVGTRKAMS MAVRNQDVNQ RQTALDFLLQ GEAELYID
//
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