ID A0A1W2BK76_9FLAO Unreviewed; 702 AA.
AC A0A1W2BK76;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SAMN05660703_2476 {ECO:0000313|EMBL:SMC73345.1};
OS Cellulophaga tyrosinoxydans.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Cellulophaga.
OX NCBI_TaxID=504486 {ECO:0000313|EMBL:SMC73345.1, ECO:0000313|Proteomes:UP000192360};
RN [1] {ECO:0000313|EMBL:SMC73345.1, ECO:0000313|Proteomes:UP000192360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21164 {ECO:0000313|EMBL:SMC73345.1,
RC ECO:0000313|Proteomes:UP000192360};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; FWXO01000004; SMC73345.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2BK76; -.
DR STRING; 504486.SAMN05660703_2476; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000192360; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR029491; Helicase_HTH.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF14493; HTH_40; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SMC73345.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000192360}.
FT DOMAIN 31..197
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 218..371
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 522..602
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 702 AA; 78984 MW; 99A84A062B8493F4 CRC64;
MPAIDYKEQL LPNLKKYFGY DSFRPQQEAI ISSVLEKKDA IVIMPTGGGK SICYQLPSLL
FPKSTLVVSP LIALMKDQVD GCIANGIAAA YFNSSQSTEE QQNILLKISK AELKLLYVAP
ESMASLEHIL NETYISCIAI DEAHCISSWG HDFRPSYQQL GFLKKSMPNT PIIALTATAD
KATRQDIAEQ LGIISAEQFI TSFDRKNISL TVRPADGRVD QIISFIEDRP NSSGIIYCLS
RKTTEQLVDR LKAKKMNAQA YHAGLSFDER TKVQEDFIFD KTKIVCATVA FGMGIDKSNV
RWVIHYNMPK NIEGYYQEIG RAGRDGVAAS ALLFHSYADV IQLQRFTEGA SNQEVQLAKL
DRMKQFSEAT TCRRKILLSY FGELLAENCG NCDVCKSPPQ VFDGTIIAQK ILSTIARLNE
KEAIGTIIDV LRGAKNAAIL EKGLEKVKTY GIGNDISWKD WQHYIIQLIN QGYIEIAFQF
RNALHLTDFS KNVLFNGAKV SLTKPIVVVE TIGNPKEKTK KSSSKGALFQ RLKALRHSIA
LEENIPAYLV FSDATLQEIE QNRPLSDEEF LEINGVGQRK LEVYGDQFIK EIIAFNKEKK
SKKADTHKVT YELYQQGLSI DEIAIKRNLK TPTIYSHIAK LYGDGLPINI YDFVTKTEVE
SVKKAKEVLE SPPSLKPYFD YFEEQLDYFK IRLALAILDK KA
//
