ID A0A1W2BY97_9PSEU Unreviewed; 519 AA.
AC A0A1W2BY97;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Serine protease, subtilisin family {ECO:0000313|EMBL:SMC77724.1};
GN ORFNames=SAMN05660733_01635 {ECO:0000313|EMBL:SMC77724.1};
OS Lentzea albidocapillata.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=40571 {ECO:0000313|EMBL:SMC77724.1, ECO:0000313|Proteomes:UP000192840};
RN [1] {ECO:0000313|Proteomes:UP000192840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44073 {ECO:0000313|Proteomes:UP000192840};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
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DR EMBL; FWYC01000005; SMC77724.1; -; Genomic_DNA.
DR RefSeq; WP_030481558.1; NZ_JOEA01000030.1.
DR AlphaFoldDB; A0A1W2BY97; -.
DR STRING; 40571.SAMN05660733_01635; -.
DR eggNOG; COG1404; Bacteria.
DR eggNOG; COG4935; Bacteria.
DR OrthoDB; 9766923at2; -.
DR Proteomes; UP000192840; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04077; Peptidases_S8_PCSK9_ProteinaseK_like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR034193; PCSK9_ProteinaseK-like.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..519
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010705122"
FT DOMAIN 399..519
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT ACT_SITE 154
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 187
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 342
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 519 AA; 53110 MW; 2D0B6E6214FC5D9A CRC64;
MRLDRTTRVL AAAGLGLAVA AAVSSPVSAQ TGSIQKSDKP VAGSYIVVFK DGATDVPTTN
AKALGLARKH GGKVSNTYVA SVRGFAVKLD EAAARRLAAD PSVAYVQQDG WASISDTQTN
PTWGLDRIDQ ANLPVDQKYT YPNTAPTVTA YILDTGIYKA HSDFEGRATD GYDFIDNDPD
ASDCQGHGTH VAGTVGSKTY GVAKKVNLVG VRVLDCSGNG QYSQIIKGID WVAQNAKKPA
VANMSLGGGA DSTVDSAVQR AIATGVTFGL AAGNNNGNAC NTSPARVPEG ITVAASDSAD
KRSIYTGGQA SNWGSCVDLF GPGSNITSTR NGGGTTSMGG TSMATPHVVG AAALYLSANP
SATPAQVRDA LVNNATTGKI TDLQGSPNKL LNISFIGGGG PDPECPAATN GDDVSIPDTN
TAVTSSVSVT GCTGKASATT KVKVDINHPY TADLAIDLVG PSGATYSLKK AKGATSSAGV
HETFTVDASA ENRDGTWKLQ VTDVWTYDAG NIDTWTLTF
//
