ID   A0A1W2CVP7_9RHOB        Unreviewed;       357 AA.
AC   A0A1W2CVP7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:SMC89299.1};
GN   ORFNames=SAMN06295998_109102 {ECO:0000313|EMBL:SMC89299.1};
OS   Primorskyibacter flagellatus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Primorskyibacter.
OX   NCBI_TaxID=1387277 {ECO:0000313|EMBL:SMC89299.1, ECO:0000313|Proteomes:UP000192330};
RN   [1] {ECO:0000313|EMBL:SMC89299.1, ECO:0000313|Proteomes:UP000192330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.12644 {ECO:0000313|EMBL:SMC89299.1,
RC   ECO:0000313|Proteomes:UP000192330};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00010398}.
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DR   EMBL; FWYD01000009; SMC89299.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2CVP7; -.
DR   STRING; 1387277.SAMN06295998_109102; -.
DR   OrthoDB; 9803687at2; -.
DR   Proteomes; UP000192330; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SMC89299.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192330};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SMC89299.1}.
FT   DOMAIN          21..279
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
SQ   SEQUENCE   357 AA;  38144 MW;  742A748CDF8700A2 CRC64;
     MTRTIVESKS KTAVIGFDEP FCVIGERINP TGRKILSEEL ERDDFSRVEA DAIAQAAAGA
     NILDVNSGAV FSNKMAEDPR YADNNFVEPM LMPEMIRRIQ AVTDTPLCID SSVPGALKAG
     LEACEGRPLL NSVTGEEERL EMVLPLVKQY NVPVVAISND DTGISEDPDV RFAVAKKIVE
     RAADFGIPAH DIVVDPLVMP IGAMATAGLQ VFALVRRLRD ELGVNTTCGA SNVSFGLPNR
     HGINNAFLPM AMGAGMTSAI MNPVALAVNQ TKIAEKKAQV MAAGIILPDD IDDETFVTLF
     GLGSTLPRPG KEMEAIRAAN LLTNNDAHGG SWIQFNKVGA TAGEATSGRR GGRRRRA
//