ID A0A1W2DIR0_9SPHI Unreviewed; 734 AA.
AC A0A1W2DIR0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN04488101_1074 {ECO:0000313|EMBL:SMC96866.1};
OS Pedobacter nyackensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=475255 {ECO:0000313|EMBL:SMC96866.1, ECO:0000313|Proteomes:UP000192678};
RN [1] {ECO:0000313|EMBL:SMC96866.1, ECO:0000313|Proteomes:UP000192678}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19625 {ECO:0000313|EMBL:SMC96866.1,
RC ECO:0000313|Proteomes:UP000192678};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; FWYB01000007; SMC96866.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2DIR0; -.
DR STRING; 475255.SAMN04488101_1074; -.
DR OrthoDB; 1006965at2; -.
DR Proteomes; UP000192678; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF13290; CHB_HEX_C_1; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000192678};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..734
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012868071"
FT DOMAIN 22..153
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 156..506
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 320
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 734 AA; 83190 MW; 0EC3E7214F777902 CRC64;
MKRISLAILL ICLSKLSIAQ NNIIPLPENY QSNGQLFKIN KETKIYYQNG LKEQAILLAS
ALSPATGFDF ELKEVKTLPS NGIVLMISKK ENNSKEAYKL SVNNQQVKIA GNSSAGTFYG
IQTLLQMLPA EIYNKERQKN KAWVINGAVI NDAPSYPWRG MMLDVSRYFF SKEYVLKFID
LMAMYKMNVL HFHLIDDAGW RLEIIKYPKL TAIGGWRGLG SEKTGGYYTQ KDIKEIITYA
AKRNVEVVPE IELPAHTLAA IVAYPYLGCT NQQFVMPTQH SISKEIYCVG KERTFDFLED
VFKETTALFP SKYIHIGGDE ANYSRWKECA DCQKKKAELG LKNESELQIY FNNRVQSILK
KYGKTLVGWD EAIEDGLKEK MVGMIWNNKK KISKAVEQGH SIVQSLTAYC YFDMFEKNIP
GEVQTATWVG PVSLERVYSF NPMLSDLDEK YRSQILGASG TLWADQFIHG NKLAEMTPLN
ENRSEQYFDY LALPRLSALA EVCWTPVKLK DWTAFENRMS THYQRYQNAG YGFRLPQPKL
VSNTNVDSTN TITLQNVVKG AEIRYTTDGS FPTPYSALYT QPIKVTNPSN FWAITVLNRQ
QYSLPFYFPN KYDRFKKLGV LATEWSPSNI KGKDFTILEI NATGIVNANG NFILTFQYTG
GESRLDINTI AIYKNGNKLA EETLDGYAGT STKNNSYTFN INNYETGAAF TIKANVSGQV
NNDSKGAIFI RKAD
//
