ID   A0A1W2DLA1_9SPHI        Unreviewed;       653 AA.
AC   A0A1W2DLA1;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   ORFNames=SAMN04488524_3963 {ECO:0000313|EMBL:SMC98221.1};
OS   Pedobacter africanus.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=151894 {ECO:0000313|EMBL:SMC98221.1, ECO:0000313|Proteomes:UP000192756};
RN   [1] {ECO:0000313|Proteomes:UP000192756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12126 {ECO:0000313|Proteomes:UP000192756};
RA   Varghese N., Submissions S.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWXT01000003; SMC98221.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2DLA1; -.
DR   STRING; 151894.SAMN04488524_3963; -.
DR   Proteomes; UP000192756; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192756};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          307..548
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
SQ   SEQUENCE   653 AA;  71234 MW;  D637E5575A5F3967 CRC64;
     MGIIMNQTEA IQMVNYIQMK TYRPAAYFFF TLWIGLLLTG CYKEEHFDFP GPYEEANTVN
     PDSLPFPFDK SRQAGMWLVK NGVPDYGKVL FKGYTDYYPK GDTLSWVKAS DGLHMLPHFS
     FYPLSNADHF AGDPNSYKFN WVYSKYFVPV GSGKSFYMYA KVTFGTFNST AAGLSLGKNW
     DTGGPFTFGL DGNTSTGEPG FFLDLYGKNG ITVNPALGWP TVTQVMTPGV PADMEVVIAN
     GIFYVKVNGT LVFTFKMAAE RAYFYTPQIR PWRNFVAVHD MYIESREMYT LDYAMHEYEG
     NYNKIQAPAL AKAANGDLLL FAEGRGTPAS SKERVAQNTM PVGNTDIIMK RSSDGGTTWS
     SQIQVLAGAG SNATYCFPQV LTADNGKIIL QYSSIGGSFT TNTYNYDASS QRVFQIESVD
     NGNSWSAPVE LTVFKNTAAG YIMGGAGHGI ALKSVNYNKR LVMPLTYSTN VVRVALSDDG
     GSSWRLSKVV GGSRLKQGTV AELADGRLMM VVGHTNTSPK NKLVSYSSDG GENWTAAANI
     ASDVKTGDYG HLFAGIVLKS RDGELLFVNP TNRESDAEVK NSPTYAVAAQ VFKSGNNGQA
     YSNLGPLFTR EAYFGYNAPI GLMDGVVTDD GKLVIAAEGG VESPAEGIVI YKK
//