ID   A0A1W2E3P4_9PSEU        Unreviewed;       824 AA.
AC   A0A1W2E3P4;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Transglutaminase-like enzyme, putative cysteine protease {ECO:0000313|EMBL:SMD04491.1};
GN   ORFNames=SAMN05660733_03690 {ECO:0000313|EMBL:SMD04491.1};
OS   Lentzea albidocapillata.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=40571 {ECO:0000313|EMBL:SMD04491.1, ECO:0000313|Proteomes:UP000192840};
RN   [1] {ECO:0000313|Proteomes:UP000192840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44073 {ECO:0000313|Proteomes:UP000192840};
RA   Varghese N., Submissions S.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWYC01000008; SMD04491.1; -; Genomic_DNA.
DR   RefSeq; WP_051770845.1; NZ_JOEA01000017.1.
DR   AlphaFoldDB; A0A1W2E3P4; -.
DR   STRING; 40571.SAMN05660733_03690; -.
DR   eggNOG; COG1305; Bacteria.
DR   OrthoDB; 9804023at2; -.
DR   Proteomes; UP000192840; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR021878; TgpA_N.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF11992; TgpA_N; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SMD04491.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:SMD04491.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        152..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        610..643
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        650..666
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        672..690
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          473..544
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          303..335
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          561..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          805..824
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        564..603
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  86243 MW;  26ACB027FD6D187E CRC64;
     MGSRSAPSKG AEPEWFTSAT PWIAALAVLC ASTALSGVIE GDLWLVRIGV VIVAITVTGA
     FLRATRLTPP LVAIAQVFVL LCLLTALHTR SGIFLFIPGP DALSELGDVL SESVAQVQTG
     VPPVHASPAI QALVVLAIGL VAVLVDTLAV AAAAPAASGL VLLCVFAVPA SLADEMLPFW
     TFILGAAAFA LLLAVDGQHR HEAWRGRLGS GSASGSGGSA TSVAAIAMVI ALVVGAGFTL
     VGTVGRLPGS GGGGGGKGGI GLSEMTSLRG MLNRGRSAEV FYVRGMNDPM YMRASTLAQY
     VPNKGWERGS PPGGQPARGE LPPQPGDRGE GRTTRINIEP RDWRSFWLPT YGAVRRIDTP
     DDDYQFDPKK GVIYTQRERE PASYELDTVM STPTKQALRL APAQANAVDG EYYKFDGVEQ
     QVVDLAKRIV AGATNDFDKA AALTAFFNGP TTEFQYKLET GGDITTDALT DFVLRGKIGY
     CEQFASAMAV MARVVGLPSR VAIGFTAGVP SADGSHRVIS TEDAHAWVEI FFPNYGWMTF
     DPTPVNDGRG IVPPYLRETA PGQEEVPTAN TQTESTSAST TGSAQASASP DGTDGDQGLP
     AASSQGPPTW HLWALGIVLV LAMLLSLLLV LALLGVLSAG LLGVSWARKL LIPVAAALWL
     MGAGLAAALL SWWLAVLLVV AGVVLTPLLV RAVRRRNHLL AVTALGPGAA SAAWSELMAE
     SIDRGAPVPM AETIRIAARR LAREHNLDDA GKDGLRTVIG AIERSWYSPN PAADPSLPGA
     VAAVRQSLRQ NAPLSLRARL FPKSVLKPSP TPVADTAERE PAGV
//