ID A0A1W2ERU1_9PSEU Unreviewed; 661 AA.
AC A0A1W2ERU1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=aminodeoxychorismate synthase {ECO:0000256|ARBA:ARBA00013139};
DE EC=2.6.1.85 {ECO:0000256|ARBA:ARBA00013139};
GN ORFNames=SAMN05660733_04428 {ECO:0000313|EMBL:SMD12411.1};
OS Lentzea albidocapillata.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=40571 {ECO:0000313|EMBL:SMD12411.1, ECO:0000313|Proteomes:UP000192840};
RN [1] {ECO:0000313|Proteomes:UP000192840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44073 {ECO:0000313|Proteomes:UP000192840};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the anthranilate
CC synthase component I family. {ECO:0000256|ARBA:ARBA00005970}.
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DR EMBL; FWYC01000010; SMD12411.1; -; Genomic_DNA.
DR RefSeq; WP_030476952.1; NZ_JOEA01000008.1.
DR AlphaFoldDB; A0A1W2ERU1; -.
DR STRING; 40571.SAMN05660733_04428; -.
DR eggNOG; COG0147; Bacteria.
DR eggNOG; COG0512; Bacteria.
DR OrthoDB; 3518032at2; -.
DR Proteomes; UP000192840; Unassembled WGS sequence.
DR GO; GO:0046820; F:4-amino-4-deoxychorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005802; ADC_synth_comp_1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00553; pabB; 1.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF18; AMINODEOXYCHORISMATE SYNTHASE; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF56322; ADC synthase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 3: Inferred from homology;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 4..186
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT DOMAIN 223..353
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 393..646
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT ACT_SITE 82
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 171
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 661 AA; 71664 MW; 4598C8EE7F491E69 CRC64;
MRTLLIDNYD SFTFNLFQHL AEVNGAEPVV VHNDDPRFRL ASLRSFDHVV ISPGPGRPGN
PADFGICRAV IDHAEIPLLG VCLGHQGLCL SYGAVVGPAP VPRHGIISPV THTGVDVFAG
LPSPFDVVRY HSLAVTELPS SLEAIAWSDD SVLMGVRALD RPAWGVQFHP ESICTDFGRE
MLANFAALTP TRTAAVPEPV LVRPTPQKRP VHVRKLAVAV NAEEAFAALH RASETAFWLD
SGPGGRFSFM GDASGPLARI AQYSVQDQVL TLDGTPRPCP SFFSWLDDDL ASWSVEQPDV
PFDFALGWVG YLGYELKVEC GGDFAHRAEQ PDASFVFTDR AVVIDHADDC VYLLSLSDDG
WFDEVSAVLA QLTPMAEPSR PVVSDVTLRH PRAHYLKLIS ACQEAITAGE TYEACLTNMM
SWRASLDPWD TYRLLRAANP VPFGALLRFG DLSVLSTSPE RFIKVDRDGV VESSPIKGTR
PRGVDAADDE MLRTTLARSV KDRAENLMIV DLVRNDLGMC AEVGSVEVTR LFEVETYATV
HQLVSTVRAR LRPDSSAVRC VRAAFPGGSM TGAPKIRTMQ ILDGLEAGPR GVYSGALGYF
SLNGAADFSI VIRTLVSNGD RVSFGVGGAV ISLSDPDEEF EETAVKATAV SRLFGAHFPG
R
//
