ID A0A1W2FH66_9PSEU Unreviewed; 216 AA.
AC A0A1W2FH66;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases {ECO:0000313|EMBL:SMD21074.1};
GN ORFNames=SAMN05660733_06164 {ECO:0000313|EMBL:SMD21074.1};
OS Lentzea albidocapillata.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=40571 {ECO:0000313|EMBL:SMD21074.1, ECO:0000313|Proteomes:UP000192840};
RN [1] {ECO:0000313|Proteomes:UP000192840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44073 {ECO:0000313|Proteomes:UP000192840};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FWYC01000014; SMD21074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2FH66; -.
DR STRING; 40571.SAMN05660733_06164; -.
DR eggNOG; COG0664; Bacteria.
DR Proteomes; UP000192840; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567:SF79; CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR CRP; 1.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR PRINTS; PR00034; HTHCRP.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SMD21074.1};
KW Transferase {ECO:0000313|EMBL:SMD21074.1}.
FT DOMAIN 6..108
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 139..208
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 216 AA; 23465 MW; 45D13E53D07F39C7 CRC64;
MIDRSFWGML DEADRAALRN TATRVEFASG SVICHQGDQS RNVLVVSRGR VRVSRFTVTG
EETVLAVRGP GEIIGELSAV DGRRRSATLT AVDAVSGLVI SPRALKSLCH VRPGITWAML
RVVASRQRAM AGQQDLRTGP SLHRVGAMLL DLAHREADDL IATVPLTQRE LAGIAGISRE
TLARTLKVLR EGGIVLTRRN GIEILREDEL RALCGI
//
