ID   A0A1W2H0D3_9BACT        Unreviewed;       420 AA.
AC   A0A1W2H0D3;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Kef-type K+ transport system, membrane component KefB {ECO:0000313|EMBL:SMD41956.1};
GN   ORFNames=SAMN00777080_0492 {ECO:0000313|EMBL:SMD41956.1};
OS   Aquiflexum balticum DSM 16537.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Aquiflexum.
OX   NCBI_TaxID=758820 {ECO:0000313|EMBL:SMD41956.1, ECO:0000313|Proteomes:UP000192333};
RN   [1] {ECO:0000313|EMBL:SMD41956.1, ECO:0000313|Proteomes:UP000192333}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16537 {ECO:0000313|EMBL:SMD41956.1,
RC   ECO:0000313|Proteomes:UP000192333};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; LT838813; SMD41956.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2H0D3; -.
DR   STRING; 758820.SAMN00777080_0492; -.
DR   OrthoDB; 9793589at2; -.
DR   Proteomes; UP000192333; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR   PANTHER; PTHR43562:SF3; SODIUM ION_PROTON EXCHANGER (EUROFUNG); 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192333};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        320..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        384..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          19..404
FT                   /note="Cation/H+ exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
SQ   SEQUENCE   420 AA;  45829 MW;  89001B0471F5A2DC CRC64;
     MENLTHQDVV NLLLQLAAML LLARVFAEIA QRFRQPAVVG ELLAGILLGP TILGTIVPDL
     HEYLFMSNPS ANLALDGFVQ IAVVLLLFIA GLEVELHLVW SQGKSALSIS LLGLVVPFAL
     GFVFPYYFSS FFGLADGDRL LFSLFMGTAM SITALPVVVR ILMDMDLFKT KMGMLIVASA
     MVNDIIGWLI FSVILSFMGK SSNLSLFQTI GITLLFTFFM LTLGKLIINR VLPWVNKKLA
     WPGGVLSLSM AFCFLAAAFT EWLGIHAIFG AFLLGVALGD SEHMSERAKE IVHQFINNIF
     APLFFVSIGL KINFFTNFEL MLTLAVLVIS FAGKIIGSGY GAFKGGFNIR ESLAVGFGMN
     ARGAMEIILG LIALENGLID EKLFVALVVM AIITSMTSGP LMKWALNPVK LERKSPKPDD
//