ID   A0A1W2H689_9BACT        Unreviewed;      1027 AA.
AC   A0A1W2H689;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Sortilin, neurotensin receptor 3 {ECO:0000313|EMBL:SMD44401.1};
GN   ORFNames=SAMN00777080_3022 {ECO:0000313|EMBL:SMD44401.1};
OS   Aquiflexum balticum DSM 16537.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Aquiflexum.
OX   NCBI_TaxID=758820 {ECO:0000313|EMBL:SMD44401.1, ECO:0000313|Proteomes:UP000192333};
RN   [1] {ECO:0000313|EMBL:SMD44401.1, ECO:0000313|Proteomes:UP000192333}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16537 {ECO:0000313|EMBL:SMD44401.1,
RC   ECO:0000313|Proteomes:UP000192333};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT838813; SMD44401.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2H689; -.
DR   STRING; 758820.SAMN00777080_3022; -.
DR   OrthoDB; 9757809at2; -.
DR   Proteomes; UP000192333; Chromosome i.
DR   CDD; cd15482; Sialidase_non-viral; 2.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 1.
DR   SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 1.
PE   4: Predicted;
KW   Receptor {ECO:0000313|EMBL:SMD44401.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192333};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1027
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012777466"
FT   DOMAIN          128..253
FT                   /note="Sortilin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15902"
FT   REGION          522..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1027 AA;  114183 MW;  AF9FDB6764B670F2 CRC64;
     MSKKFYFNFL VVFFCLIASG SFAQENITLK GNELFGSLSA RQIGPAVMSG RISDIAGHPT
     NNRIIYAGTA GGGVWKSTNG GTTFRSIFDD YNQSIGIIEV DPNNPDNVIW VGTGETWVRN
     SVSFGDGLYK TVDGGNTWNK IGLENSDRIS GIAINPNNSD EVYVGVLGAL WGDSDERGVY
     KTTDGGQTWT NILAGMKDTG CSDLFMDPKD PNTLYAAFWQ VRRTAYSFSS GGPNSALYKT
     KDGGKTWDKI HNGFPTGDLG RIAIALAPSE PSILYSVIES KDKKGLYRSE DAGNSWTFMN
     GDFELTVRPF YFSRIVVDPK NPDVLVKAGL SGSISRDGGK TFKSLGPMHA DIHDIWFDIN
     DSDRFYVATD GGLYRTWDGG TTLEMVESLP VSQFYHVSLD NDEPYRIYGG LQDNGSWFGP
     SASPGGIEPG DWVSVGAGDG FRVYRHPTKK IVYSEMQGAD NIWRYDVEKN VIKNIRPFPG
     KDEPKYRFNW NTPIQISPHH PDRFYVGSQF LLRSNDMGNN WERISPDLTT NDPAKQNQSS
     SGGISTDNSG AENHTTIFTI AESPLDENII WVGTDDGNVQ VTQDGGKTWT NVVSNIPDLP
     KNTWTYHIQP GNFGKGTAYA VFDGHSQNDF KTYAYKTTDF GKTWNSVISD DVHGFARHIL
     EDLENENLLF LGTELGLFVS IDGGKNWSKF TNNMPAASVH YMAMHPKTND LVLATHGRGI
     IIIDDISPLR QIKPQMLNEE VYFLKSPPIV MWEERNFGGS SQAITFVGPN PNKSGKIVYY
     LKKRHTFGAM TLEIFDKNDS KVISLDPGKQ KGINIVRWNF TGKAPKVAKG KTFSSGGSGA
     PRVPAGTYKV VMKKGKEQFE TTLELVYDDR TGIAVESRKA QQKVANELFD MTQDLAYLVY
     QVDSYLDYAE KIKTADPKSN KSMTALINDL NKLKETLVIT TGDNYVDTAE PELREKISQL
     YGIVIANFDR PSVIQEENKN TLNEKLKESQ NTFINILSKH EKNLLRYAKS ANMENLILDD
     FVTFIEK
//