ID   A0A1W2H8A6_9BACT        Unreviewed;       636 AA.
AC   A0A1W2H8A6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   31-JUL-2019, entry version 12.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SMD45125.1};
GN   ORFNames=SAMN00777080_3767 {ECO:0000313|EMBL:SMD45125.1};
OS   Aquiflexum balticum DSM 16537.
OC   Bacteria; Bacteroidetes; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Aquiflexum.
OX   NCBI_TaxID=758820 {ECO:0000313|EMBL:SMD45125.1, ECO:0000313|Proteomes:UP000192333};
RN   [1] {ECO:0000313|EMBL:SMD45125.1, ECO:0000313|Proteomes:UP000192333}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16537 {ECO:0000313|EMBL:SMD45125.1,
RC   ECO:0000313|Proteomes:UP000192333};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT838813; SMD45125.1; -; Genomic_DNA.
DR   BioCyc; GCF_900176595:B9A52_RS18565-MONOMER; -.
DR   Proteomes; UP000192333; Chromosome i.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 1.25.40.10; -; 2.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR041617; TPR_MalT.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF17874; TPR_MalT; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50005; TPR; 3.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00776324};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000192333};
KW   Kinase {ECO:0000256|SAAS:SAAS00529081, ECO:0000313|EMBL:SMD45125.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00777800};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192333};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transferase {ECO:0000256|SAAS:SAAS00529055};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    361    382       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       90    203       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   REPEAT       90    123       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      130    163       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      170    203       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   DOMAIN      422    636       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
FT   COILED      336    356       {ECO:0000256|SAM:Coils}.
FT   COILED      385    415       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   636 AA;  73726 MW;  80C311743C480574 CRC64;
     MYNLTIKVKF LLLLFLIFAF RNESLVSQSF DVSQKAENIL AQYQNAKSDR LKLDLISQLV
     RVIHYTDSAQ KYYPEAIRLA RLVGDAELEA QNLNRLGVYY RNMNLQEEAL KLYEEALSIS
     KNADIPVQIG HSLNNIGQIF FYQDQFQESL NYYLEAEKKF LEIGDKEGLA YNYNGMSLVL
     AEIRDFEQAL ETINKAIKIR EELGNERQLT VSKFNRADIL MSMGDYANAE PDIMNLYDYG
     MANDKIRAIN ALEKLVELKL KTYRFSQAVT YAKEAMVLHD EKPFSESIIE IYQMMYQYFF
     DRGNTIESKK YLSLLESERN RLNEIKTKNY LAGLTIKKQR DEIASLQREK ELMEINDRFK
     FYLSIVLFLL AFAMFVAFSI YYRYYLKQKE NLIQLKEKQK QIEAQANELD RLNIVKDKIF
     SILAHDLKAP MDSLWGMIKL IDEENLTQSE FEEYLPILSQ NLGNNSILLE NLLIWSRSQM
     KGMNVQISRI NLFKLVEENI RFLLSSGFYK GQVVENYVAE NIEVEADKNM IDIVFRNLLT
     NALKFTKEGD QIIVDIKESD NVYTVCVSDQ GTGISEEGLK KLFGKDFHST NGTHQEKGTG
     LGLILTKELV QKNKGEIWAE STLGMGSTFC FTLPKM
//