ID A0A1W2TDE4_ROSNE Unreviewed; 998 AA.
AC A0A1W2TDE4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=SAMD00023353_0301210 {ECO:0000313|EMBL:GAP86005.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP86005.1};
RN [1] {ECO:0000313|EMBL:GAP86005.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP86005.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
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DR EMBL; DF977448; GAP86005.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2TDE4; -.
DR STRING; 77044.A0A1W2TDE4; -.
DR OMA; VDVMFHR; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:GAP86005.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516}.
FT DOMAIN 314..477
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 499..674
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 950..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 998 AA; 112747 MW; 5A2E7A99C3A89D2B CRC64;
MDRKEGNFSP KRRKLDFNPL RSDDRYSSLP ARSHNASRPH SRALNATSSR ASTPRNQSSY
AATPKPDESN GPGPSVSHED QLALDRDWYG GDETGGHTFG DDSHNPFGSY DTSWVEQQQR
EAQMVEKKAG RQMNARQLQR QKDNDAWETN RMLTSGVAQR RGLGDDFDDD NEGTRVHLLV
HDLKPPFLDG RTVFTKQLEP VPAVRDYQSD MAVFSRKGSR VVKERRQQRE RQRQAQDATN
MAGTTLGNLM GVKEEEGDSA LPIAAEDDQA NKGGGNKFSE VMKKNDGASN FSQSKTLREQ
REFLPAFAVR EDLLRVIRDN QVVIVVGETG SGKTTQLTQF LYEDGYGKRG MIGCTQPRRV
AAMSVAKRVA EEMEVKLGST VGYAIRFEDC TSKDTVIKYM TDGVLLRESL NERDLDRYSC
VIMDEAHERA LNTDVLLGLF NKILQRRRDL KLIVTSATMN SKRFSDFFSG APEFTIPGRT
FPVDIMFHRS PVEDYVDQAV QQVLSIHVSM GSGDILVFMT GQEDIECTCE LVRERLDALN
DPPELSILPI YSQMPADLQA KIFDRAPPGV RKCIVATNIA ETSLTVDGIM YVVDAGYSKM
KVYNPRMGMD TLQITPISQA NAGQRAGRAG RTGPGRAFRL FTEKAFKDEL YIQTIPEIQR
TNLSNTVLLL KSLGVRDLLD FDFMDPPPQD TITTSMFDLW ALGALDNLGE LTDLGSKMNA
FPMDPSLAKL LIMSEEYGCS EEMVTIVSML SVPNVFYRPK ERQEESDAAR EKFFVPESDH
LTYLHVYSQW KSNGYSDGWC TRHFLHPKSL RRAKEIRDQL LDIMKMQKME MISCGTDWDI
IRKCICSGYY HQAAKVKGIG EYINLRTSVT VQLHPTSALY GLGFLPDYVV YHELILTSKE
YMSTVTSVDP HWLAELGGVF YSVKEKGYSA REKRVTETEF NRKIEIETKM AEDKRRQEEQ
QKAEQEKSVK KPVAEKTRKI ITSGAVKKLA LKRKGRGF
//
