ID A0A1W2TDW4_ROSNE Unreviewed; 2220 AA.
AC A0A1W2TDW4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Putative sec63 brl domain-containing protein {ECO:0000313|EMBL:GAP86182.1};
GN ORFNames=SAMD00023353_0303150 {ECO:0000313|EMBL:GAP86182.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP86182.1};
RN [1] {ECO:0000313|EMBL:GAP86182.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP86182.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF977448; GAP86182.1; -; Genomic_DNA.
DR STRING; 77044.A0A1W2TDW4; -.
DR OMA; QTEIQYY; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18019; DEXHc_Brr2_1; 1.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516}.
FT DOMAIN 550..734
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 769..981
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1402..1578
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 195..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..240
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2220 AA; 250520 MW; 3E1AF47D5B5579C8 CRC64;
MADHHRDVSQ YKYSAMSNLV LQADRRFITR RTDEATGDPE SLAGRLNVND MGSRITRDAA
PKTARKKTLA VERGDAQEGQ DILAREQKKR RNNALQLKGA GILGQADLLV EGLRYQPRTP
ATRATFDLML HLVASNLGDV SHEVVLSAAD AALEYLKDED MKDIEKKKEI DDLIGTSLNP
KQFNELVNLG KKITDYDTQN DDEDMDADAG RDELDGELDD RQGVAVVFDE EDEDEEAAMV
NEVRDESSDD EAPSDDDEQN ITGIGGRETA ADAGEDRDRE VPGLPDGDAM VIDPGISESK
TKAASEGKNY IAARDIDAYW LQREIGNLYS DAHIQHDKTA DALHILSGEP DGPDGEEKQL
REIENDLMEL FDYEHHEIVQ KLIENREKIV WLTRLAKAED AENRGVIERE MASEGLRWIL
DELRGKKASD GTKKMEIKMD IDVPAALTDA PKSGKADGQL VGGLQPRKYI NLENLVFDQG
NHLMTNPKVR LPEGSTKRTF KGYEEIHVPA PNKRNQPNDV SIPITDMPEW AQGPFSSAKA
LNKIQSKCYP SAFEDDGNML ICAPTGSGKT NVAMLTILRE LGKHRNPQTG DIDLDAFKIV
YIAPLKALVQ EQVGNFGARL KAFGITVSEL TGDRQLTKQQ VTETQVIVTT PEKWDVITRK
ATDLTYTNLV RLIIIDEIHL LHDDRGPVLE SIVSRTIRKT EQTGDPVRLI GLSATLPNYR
DVASFLRVDL DKGLFHFDGS FRPCPLKQEF IGVTDKKAIK QLKTMNDITY NKVIEHVGTH
HNQMLIFVHS RKETAKTARY IRDKALEMET INQILKHDSG SREALNEIVS DISDADLKDL
LPYGFGIHHA GMNRVDRDEV EGLFSAGLIQ VLVCTATLAW GVNLPAHTVI IKGTQVYSPE
KGSWVELSPQ DVLQMLGRAG RPQYDTYGEG IIITSQNEMQ YYLSLLNQQL PIESQFASKL
VDNLNAEIVL GNVRNRDEGV EWLGYTYLFV RMLRSPGLYS VGADYEEDEA LEQKRVDLIH
SAAVVLKKAN LVTYDEKTGK LKGTELGRIA SHYYITHGSM DTYNKLIQPS ITTIELFRVF
ALSAEFKYIP VRQDEKLELA KLLGRVPIPV KESIEEPHAK INVLLQAYIS RLKLDGLALM
ADMVYVTQSA GRILRAIFEI TLQKGWSSVC RTALDLCKMA EKRMWPTMTP LRQFGPRCSR
DIVAKAERID VPWSSYFDID PPRMGELLGI PKAGRIVCDL VSKFPRLDIQ AQAQPITRSM
LRIELSITPN FEWDDEIHGT TESFWIMVED CDGEDILFQD QFLLRKDYAV SESNEHMVDF
TVPITDPMPP NYFISVVSDR WMHSETRLPI SFEKLILPEK FPPHTQLLDL QPLPVAALKA
KDYSSLYDGW NYFNKIQTQT FNSLYGADDN VLIGAPTGSG KTVCAEFAVL RLWSKAEIGR
AVYIAPSQEL VDIRYQDWQK RLSHLRGGKD IVKLTGETAI DLKLLEKGDL ILATPSQWDV
LSRQWQRRKN ILTVELFIAD ELHLLGGPLG YVYEIIVSRM HYIRTTANLA MRIIGLSVSL
ANARDLGEWV DAKKKDIYNF SPHVRPVPLE LRLQSYTIPH FPSLMLAMAK PTYLAITELS
ADQPALVFVP NRKQTRSTAR DILTACLADD DEDRFLHVDS DQLRPLLEHI HEDALAEALS
HGVGYYHEAL SQNDKRIVIH LYKQGAVQIL IASRDTCWEL DCAAHLVIVM GTQYFEGREH
RYIDYQLSEV LQMLGKALRA SGDGRSRAVL MTSAIKREYF KKFLNEALPV ESHLHNYVHD
AFVTEISTKM IESTEDAINW TTFTYFYRRL LANPSYYSLT SPTHDGLSNY LSDLVETTIK
ELTESKIIDF DEDDGSVSPQ NAAMIAAYYN LSYITMQTFL LSLSAKTKLK GILEIVTSAT
EFESIQIRRH EDSLLRRIYD RVPVKMSEPA YDSPHFKAFV LLQAHFSRMQ LPIDLSKDQE
IIISKVLSLL SATVDVLSSD GHLNAMNAME MSQMVVQAMW DRDSPLKQIP HFSPDVVKVA
NEFKVNDIFD FMEAMNPEEN KDYSDFVKRL GLSQAQLAQA ATFTNTKYPD ISLEFEVLDG
DNIHAGEPAY LNVQIEREVE GEEDEVDTTV HAPFYPAKKV ENWWLVVGEE TTKTLLAIKR
VTIGRQLKVR LEYTVPTPGQ HDLKLFLMSD SYIGVDQEPT FSVNVAEGMD LDEDEEDDDE
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