ID A0A1W2THM6_ROSNE Unreviewed; 537 AA.
AC A0A1W2THM6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Putative ubiquitin thiolesterase {ECO:0000313|EMBL:GAP87637.1};
GN ORFNames=SAMD00023353_0901150 {ECO:0000313|EMBL:GAP87637.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP87637.1};
RN [1] {ECO:0000313|EMBL:GAP87637.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP87637.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DF977454; GAP87637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2THM6; -.
DR STRING; 77044.A0A1W2THM6; -.
DR OMA; NKFVAER; -.
DR OrthoDB; 719409at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000245; P:spliceosomal complex assembly; IEA:InterPro.
DR CDD; cd02669; Peptidase_C19M; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR033809; USP39.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR21646:SF16; U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 77..174
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT DOMAIN 199..528
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 61284 MW; 878E0A81EED77B43 CRC64;
MSKRQASEAL DELHGVDSPA SKRSRFDEGP ESNGTAIATD PEDSIADIES DDGHDHGYDY
DEPAKAPIRQ SAPTEGYGDL YLDTIDRNVL DFDFEKLCSI SLSNINVYAC LVCGKYFQGR
GPKSHAYFHA LGDGHHVFIN MEAQKVYVLP EGYEVRSKSL DDIKYVSDPR YSREEVMGLD
RKPRTAWTLD GKQYTPGYVG MNNIKENDYL NVVVQALSHV EPLRNFFLLE DFSSRPELVR
RCAILFRKIW NARAFKSHVS PHELLQEISL RSNKKFTLTE QSDPVDFLSW FLNNLHLGLG
GSKTKPGSSI IQRIFQGKLK VESQAITAKA DVGDRLRFEE AAEVKADISR FLLLTLDLPP
APLFQDDMEG NIIPQVPLTT ILSKYDGVKA QEHLAQRKRY RLMHPLPPYL IFHIKRFSKN
KFVSERNPTI VTFDARIGLD VSPYVEPSPV NHPPGEPIWY DLVANVTHEA VRAKEDVADT
GEERKTWKVQ LKDKGRDEWV VCQDLFVEGI QKELLYLGES YLQVWERRRD PKGKQKR
//
