ID   A0A1W2TIG7_ROSNE        Unreviewed;       762 AA.
AC   A0A1W2TIG7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Putative VTC domain-containing protein {ECO:0000313|EMBL:GAP87959.1};
GN   ORFNames=SAMD00023353_1600400 {ECO:0000313|EMBL:GAP87959.1};
OS   Rosellinia necatrix (White root-rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX   NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP87959.1};
RN   [1] {ECO:0000313|EMBL:GAP87959.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W97 {ECO:0000313|EMBL:GAP87959.1};
RA   Kanematsu S.;
RT   "Draft genome sequence of Rosellinia necatrix.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC       {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004128}.
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DR   EMBL; DF977461; GAP87959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2TIG7; -.
DR   STRING; 77044.A0A1W2TIG7; -.
DR   OMA; AAWGWYM; -.
DR   OrthoDB; 11387at2759; -.
DR   Proteomes; UP000054516; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd14480; SPX_VTC2_like; 1.
DR   Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018966; VTC_domain.
DR   InterPro; IPR042267; VTC_sf.
DR   PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR   PANTHER; PTHR46140:SF2; VACUOLAR TRANSPORTER CHAPERONE 2-RELATED; 1.
DR   Pfam; PF02656; DUF202; 1.
DR   Pfam; PF09359; VTC; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT   TRANSMEM        674..696
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        717..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..151
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   REGION          83..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          504..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          554..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..522
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        559..573
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   762 AA;  87699 MW;  A682E319020A90A3 CRC64;
     MRFGKTLRGS IYPPWKDEYI DYPKLKGMLR ENTGDDDDAP WTEDDENRFC DEIFNVQLDK
     VSQFQAKRAS SLQQRADAAF EKLRELAPSD DKPKSDTTNS RLEELRSELD TIVNEVKELK
     KYSNLNYTGF LKIAKKHDRK RGDRYKVRPM MRVSLSEHGL NSEQGYSPLL NKLSLMYYAI
     NQTLDKDKQQ QLPDLEYQEE VHNGERYTAH KFWVHPDNLL EVKTAILRHL PALVYSQQAA
     KELDGNEDPK ITSLYFDNPK FALYGAKVSR QVDASSVRLR WYGQLNEKPD IMLEQKVVYE
     DGTSEEKRFN IKDKYTKQYL DGEYKMEKSI QKMERQRQQN DSIGLFKATA EDIQNFIVTN
     KLQPVMRANY TRTAFQKPAD DRVRISIDTD IAFIREDTLD RDRPCRDPAE WHRTDIDNSN
     MTYPFKNINQ SEVSRFPYAV LEIKSKEQEG RKRPRWIDDL IGSHLVYATP KFSKFVHGVA
     SLFEDYVNNL PFWLSDLETD IRKDPHKAHE EEEQRRARQA EDALAVDNLL GTSARRSSYR
     TGVGSPVAKS YLSERAASEA RTSRMRPADE SSEMAGEADD ENVGAESGLR RGYGTLSSVF
     PGFSLSRYAQ NKRQKEQLPK GVTKPDVWLK NMGPLQIEPK VWLANERTFL KWQHICVLLG
     TLALGLYTAA GENLVAECMG IAYIVIAISA GLWGNMMLHR RRAMIIERSG KDFDNMIGPL
     LISVALMVAL ILNFVFAYRN ALGKFDGPIR NETETAFIGE LL
//