ID   A0A1W2TIZ2_ROSNE        Unreviewed;       256 AA.
AC   A0A1W2TIZ2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Putative dihydrodipicolinate synthetase protein {ECO:0000313|EMBL:GAP88169.2};
GN   ORFNames=SAMD00023353_1500540 {ECO:0000313|EMBL:GAP88169.2};
OS   Rosellinia necatrix (White root-rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX   NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP88169.2};
RN   [1] {ECO:0000313|EMBL:GAP88169.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W97 {ECO:0000313|EMBL:GAP88169.2};
RA   Kanematsu S.;
RT   "Draft genome sequence of Rosellinia necatrix.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; DF977460; GAP88169.2; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2TIZ2; -.
DR   STRING; 77044.A0A1W2TIZ2; -.
DR   OMA; PVVCNGI; -.
DR   OrthoDB; 1780992at2759; -.
DR   Proteomes; UP000054516; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   PANTHER; PTHR12128:SF47; DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G01230); 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054516}.
FT   ACT_SITE        142
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        172
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         215
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   256 AA;  26984 MW;  694D663687A342CA CRC64;
     MAPSKVPPSG IWAPAITFFD PETDTLLPSD QAKYYAYLSR TGLAGLVILG TNAETFLLTR
     EERRQLVQVA RAACGPGFPL MAGVGGHSTR QVLEFVGDAA EAGADYALVL PPAYFGKATT
     PAVVDGFYAE VAARSPLPVV VYNFPGVCNG VDLDSAAVAR LARRHDNVVG VKLTCGSVAK
     ITRLAAELPP GRFATFGGQS DFLVGGLSSG SAGCIAAFAN VFPRTLVRIY DLYRQGRHAE
     ALDLHQKAAL AEQPCK
//