ID A0A1W2TMF6_ROSNE Unreviewed; 806 AA.
AC A0A1W2TMF6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 03-MAY-2023, entry version 20.
DE RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN ORFNames=SAMD00023353_3800250 {ECO:0000313|EMBL:GAP89509.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP89509.1};
RN [1] {ECO:0000313|EMBL:GAP89509.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP89509.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560}.
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DR EMBL; DF977483; GAP89509.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2TMF6; -.
DR STRING; 77044.A0A1W2TMF6; -.
DR OMA; PEDGAWF; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotidyltransferase {ECO:0000313|EMBL:GAP89509.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW Transferase {ECO:0000313|EMBL:GAP89509.1}.
FT DOMAIN 470..765
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 86951 MW; C24EF7575C233346 CRC64;
MQNANKGSRV APIFPPKTPA PASSNLIPSS SPAFGTPAHT LKPFSIAPPS KATILPILLP
PATLRPLAFR TFTKKHSLTL ASTALQELAT FIGRHCGSGW REEGLAEKVL EEVARGWKNR
NGGVIVDGSS QELKDILKTL EGNMSGGRIG AAPDLSRQNS FALDAPQESE LSNTRLGLRP
ASNLTREDTQ ASFGMSSLGV QEDEPDEEGL NHPRSWLKVV NAFDQPRMLY NISKKHFERD
PSKPSLMPPA SHKTTMFRNR YNVIHQRLLR NESFQSSSVA TTKGPPSMMR SSSSGLTTQQ
THKITPIANL LGRHGTHHML LGMLSILPAG GLAINDLTGT ISLDLSHAAA IPENSAWFTP
GMIILVDGVY EEEEESVGKG LGASNGIGGV IGGRFQAFFI GQPPCEKRKA TLGVSGPDGG
QDHTIGGGFG WIDFLGVGSE RAVGPKMRKL ERRLLRQAQP DPDLPSRGRV IIIGELNLDQ
PRALQALRKI LTTYAMEPEG SSPMTFVLAG NFTQHAVMAG GGASGGSVEY KEYFDSLASV
LTDFPTLLQS STFVFVPGDN DGWASSFSSG SAVPLPRKAV PDMFTSRIRR AFATANTEAG
ARGGMGGEAI WASNPTRLSV FGPLHEVVLF RDDMSARLRR TAIRLNTSPS SNPSADNRER
EPPPPPSRPN ADDDDIEMAS ALDNADDMDV DPSSTTGGKP KPKSPEIPHD VQTARRLVKT
VLDQGYLCPF RHTIRPVHWD YAGALHIYPL PTALVLVDPT APPFALTYEG CHVMNPGPML
VTGRRGVGRW IEYELGGVGR LRECMF
//
